Repeated neonatal handling with maternal separation permanently alters hippocampal GABAA receptors and behavioral stress responses.
about
Desperately driven and no brakes: developmental stress exposure and subsequent risk for substance abuseGABAA receptor-acting neurosteroids: a role in the development and regulation of the stress responseProlonged maternal separation induces undernutrition and systemic inflammation with disrupted hippocampal development in mice.The role of early life stress as a predictor for alcohol and drug dependenceReduced cortical BDNF expression and aberrant memory in Carf knock-out micePre-reproductive maternal enrichment influences offspring developmental trajectories: motor behavior and neurotrophin expression.Chronic stress impairs GABAergic control of amygdala through suppressing the tonic GABAA receptor currentsTransient gastric irritation in the neonatal rats leads to changes in hypothalamic CRF expression, depression- and anxiety-like behavior as adults.Mutations affecting GABAergic signaling in seizures and epilepsy.The short splice variant of the gamma 2 subunit acts as an external modulator of GABA(A) receptor function.The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependenceα2-containing GABA(A) receptors: a target for the development of novel treatment strategies for CNS disorders.Loss of leptin receptors on hypothalamic POMC neurons alters synaptic inhibition.GABAA receptor subtype involvement in addictive behaviour.Dimensional anxiety mediates linkage of GABRA2 haplotypes with alcoholism.The role of GABA(A) receptors in the development of alcoholismMaternal Separation during Breastfeeding Induces Gender-Dependent Changes in Anxiety and the GABA-A Receptor Alpha-Subunit in Adult Wistar Rats.Early and later life stress alter brain activity and sleep in rats.Lifetime stress cumulatively programs brain transcriptome and impedes stroke recovery: benefit of sensory stimulationAltered GABA signaling in early life epilepsies.Association of childhood trauma exposure and GABRA2 polymorphisms with risk of posttraumatic stress disorder in adults.Developmental emergence of fear learning corresponds with changes in amygdala synaptic plasticity.Early postnatal stimulation alters pregnane neurosteroids in the hippocampus.Effects of status epilepticus on hippocampal GABAA receptors are age-dependent.Adolescent-onset GABAA α1 silencing regulates reward-related decision making.GABA(A) receptors in normal development and seizures: friends or foes?Early life stress is a risk factor for excessive alcohol drinking and impulsivity in adults and is mediated via a CRF/GABA(A) mechanismEarly parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder.Social stress, therapeutics and drug abuse: preclinical models of escalated and depressed intake.The epileptic hypothesis: developmentally related arguments based on animal models.Blockade of androgen receptors is sufficient to alter the sexual differentiation of the substantia nigra pars reticulata seizure-controlling networkDysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress response.Early life stress as an influence on limbic epilepsy: an hypothesis whose time has come?Early-life stress impacts the developing hippocampus and primes seizure occurrence: cellular, molecular, and epigenetic mechanisms.Nonsteroidal anti-inflammatory treatment prevents delayed effects of early life stress in rats.Electrophysiological insights into the enduring effects of early life stress on the brain.Experimental medicine in drug addiction: towards behavioral, cognitive and neurobiological biomarkers.Surface expression of GABAA receptors is transcriptionally controlled by the interplay of cAMP-response element-binding protein and its binding partner inducible cAMP early repressorLong-lasting enhancement of GABA(A) receptor expression in newborn dentate granule cells after early-life febrile seizures.Basolateral amygdala and stress-induced hyperexcitability affect motivated behaviors and addiction.
P2860
Q24653305-11D09675-6DB1-4A6B-9620-F5847DA7413FQ28241963-30B299B9-FECD-4B18-AD12-6836D40EF38BQ30276843-349142D4-921D-41EB-934A-D7771C1DE76AQ30470117-021F754E-D13A-49A5-84BD-D09DE9C0DD95Q30495151-19745E43-C316-47A4-9A2D-D13B2BEB00BEQ30579235-5CD785DB-A301-4ECF-86C3-1A06164B939AQ33577017-82C7B8FF-92CB-4F27-B8BE-3CF61E1569B9Q33903930-448C3859-E8C7-479A-872A-45B24348ED7DQ33912426-CBBA519B-0470-43FF-B906-31FB89F9E669Q33937098-1D72D942-295B-48AB-BDF3-AD4717E72CBDQ34245147-C67405FC-F4ED-47D0-A111-91C77B80DB3EQ34295813-C1124C0D-80C4-400A-BD60-F1E557CB8016Q34379545-B52C3853-3F2A-4B17-BCB8-CC53464789C7Q34537848-7814C4F1-1302-4EC1-B00F-B39012C6FF72Q34569426-91BBD966-BE8B-43EB-9F56-7E30532BEE20Q34774410-D748C466-1ECA-40EC-BB9A-FD916720A8F1Q34797669-3780191E-9F04-4ED1-848B-00360C315D87Q34904828-C9AA0F85-7FF5-4AA7-8C8E-323136ABEC7DQ35126084-C58D872A-99E3-4B76-AAE0-AA03C7D8E6F2Q35147300-ABBADA37-C888-415B-86FD-6CC9F3CCDAC9Q35792779-E0680115-EBC4-4849-9E9C-B8BB24C005CAQ36535803-093902FD-0BB3-4580-9B1C-ABC4A3A3262FQ36716468-A6D8F055-4025-4041-9213-6817E2DE79A6Q36740341-5558F1EC-92AC-4EC4-B77F-2D6718F1DEEFQ36784162-3B13ED95-76B5-438E-9C3A-239A96249A30Q37104140-B45987EB-C930-4163-BA51-E723ED460174Q37129719-6C7FF80E-1E51-42E7-BC2E-8C3A4F3C483DQ37159338-61628B46-C004-4BE8-B300-399D377716AAQ37267936-3C8BD388-FE8E-489F-B82F-F763E83F18D9Q37328931-200E24C0-E3B1-460E-99B3-79020F4A5EF8Q37353664-701C8317-4270-4953-9179-C723E1D7E37CQ37381812-396A84D6-C454-4766-9747-1F83686BE0F3Q37388479-ADD2F36F-7DFA-4113-A4E3-6A16A774C988Q37571770-A174A9E1-2F82-4EF5-8A11-BD2603FFD38BQ37587452-83EB831D-1554-4471-AEB3-0860A5737DE6Q37821815-189FFBE3-3B35-46C6-AE50-4C578F8FDD46Q37822217-5C8DCE51-036A-4FA5-B115-E9F8B50DBC44Q39261495-8D7E8C65-786A-4454-9E40-77A17D9B505FQ40294475-95B14FEF-6CB4-4387-9727-993172753297Q41687551-81D7AA1E-DBE7-49E1-BCC1-DE7B691145ED
P2860
Repeated neonatal handling with maternal separation permanently alters hippocampal GABAA receptors and behavioral stress responses.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Repeated neonatal handling wit ...... d behavioral stress responses.
@ast
Repeated neonatal handling wit ...... d behavioral stress responses.
@en
type
label
Repeated neonatal handling wit ...... d behavioral stress responses.
@ast
Repeated neonatal handling wit ...... d behavioral stress responses.
@en
prefLabel
Repeated neonatal handling wit ...... d behavioral stress responses.
@ast
Repeated neonatal handling wit ...... d behavioral stress responses.
@en
P2093
P2860
P356
P1476
Repeated neonatal handling wit ...... nd behavioral stress responses
@en
P2093
Amy R Brooks-Kayal
Fu-Chun Hsu
Guo-Jun Zhang
Yogendra Sinh H Raol
P2860
P304
12213-12218
P356
10.1073/PNAS.2131679100
P407
P577
2003-10-06T00:00:00Z