Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants.
about
A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer.A Phos-tag SDS-PAGE method that effectively uses phosphoproteomic data for profiling the phosphorylation dynamics of MEK1.MIG6 Is MEK Regulated and Affects EGF-Induced Migration in Mutant NRAS Melanoma.Targeting mutant NRAS signaling pathways in melanoma.A phase I dose-escalation study of TAK-733, an investigational oral MEK inhibitor, in patients with advanced solid tumors.Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma.MEK inhibitor, TAK-733 reduces proliferation, affects cell cycle and apoptosis, and synergizes with other targeted therapies in multiple myelomaA Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family.TAK-733 inhibits inflammatory neointimal formation by suppressing proliferation, migration, and inflammation in vitro and in vivo.
P2860
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P2860
Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
@zh-my
2014年学术文章
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2014年學術文章
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2014年學術文章
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2014年學術文章
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name
Antitumor activity of the MEK ...... atient-derived tumor explants.
@ast
Antitumor activity of the MEK ...... atient-derived tumor explants.
@en
type
label
Antitumor activity of the MEK ...... atient-derived tumor explants.
@ast
Antitumor activity of the MEK ...... atient-derived tumor explants.
@en
prefLabel
Antitumor activity of the MEK ...... atient-derived tumor explants.
@ast
Antitumor activity of the MEK ...... atient-derived tumor explants.
@en
P2093
P2860
P1476
Antitumor activity of the MEK ...... patient-derived tumor explants
@en
P2093
Esha Gangolli
Heather M Selby
John J Tentler
Kelli M Robertson
Kelsey L Brunkow
Lindsey N Micel
Patrick W Vincent
Peter J Klauck
Robyn Fabrey
S Gail Eckhardt
P2860
P304
P356
10.1158/1535-7163.MCT-13-1012
P577
2014-11-05T00:00:00Z