High- and low-affinity single-peptide/MHC ligands have distinct effects on the development of mucosal CD8alphaalpha and CD8alphabeta T lymphocytes
about
Predominant clonal accumulation of CD8+ T cells with moderate avidity in the central nervous systems of Theiler's virus-infected C57BL/6 mice.Elevated T cell receptor signaling identifies a thymic precursor to the TCRαβ(+)CD4(-)CD8β(-) intraepithelial lymphocyte lineage.Optimal T-cell receptor affinity for inducing autoimmunity.Clonal deletion and the fate of autoreactive thymocytes that survive negative selection.Selection and expansion of CD8alpha/alpha(1) T cell receptor alpha/beta(1) intestinal intraepithelial lymphocytes in the absence of both classical major histocompatibility complex class I and nonclassical CD1 moleculesSelection of self-reactive T cells in the thymus.Intraepithelial lymphocytes: their shared and divergent immunological behaviors in the small and large intestine.Intestinal T cells: facing the mucosal immune dilemma with synergy and diversity.TL and CD8αα: Enigmatic partners in mucosal immunity.Controlling subcellular delivery to optimize therapeutic effectGeneration of transgenic mice expressing EGFP protein fused to NP68 MHC class I epitope using lentivirus vectors.
P2860
Q33676513-DD18D8BE-BFDA-4712-AD11-AF9FA3AAD7A3Q34301124-58188F5E-230F-407D-A7F1-93405D5C534AQ34661042-46C2D920-7FFE-4628-8F56-F62183DF9A4DQ35996079-AE625B18-FA63-42C3-BA31-2A06D10365EFQ36375329-F6A4A0F1-43D8-4718-9FC6-E3CDB07FBC02Q36456282-1BCF02EB-BE4A-4822-996F-C59EADE1AE8BQ36732679-486D7D38-91AB-4E7E-9341-9B25A6F7A42FQ37455474-24A94730-EAB3-48FF-9DAA-E81A980D60CFQ37789941-8DA6BFB9-8810-4A6C-8026-6F50178E42C2Q37813021-FC5EC541-A32D-4BD4-8342-0445AFCEE126Q46311695-8E7CF403-B1BB-48A1-98DE-BADF0A691F60
P2860
High- and low-affinity single-peptide/MHC ligands have distinct effects on the development of mucosal CD8alphaalpha and CD8alphabeta T lymphocytes
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
High- and low-affinity single- ...... and CD8alphabeta T lymphocytes
@ast
High- and low-affinity single- ...... and CD8alphabeta T lymphocytes
@en
type
label
High- and low-affinity single- ...... and CD8alphabeta T lymphocytes
@ast
High- and low-affinity single- ...... and CD8alphabeta T lymphocytes
@en
prefLabel
High- and low-affinity single- ...... and CD8alphabeta T lymphocytes
@ast
High- and low-affinity single- ...... and CD8alphabeta T lymphocytes
@en
P2093
P2860
P356
P1476
High- and low-affinity single- ...... and CD8alphabeta T lymphocytes
@en
P2093
C N Levelt
C O'Farrelly
C Terhorst
E Mizoguchi
S J Simpson
S Tonegawa
Y P de Jong
P2860
P304
P356
10.1073/PNAS.96.10.5628
P407
P577
1999-05-01T00:00:00Z