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Spontaneous cancer and its possible relationship to oxygen metabolism

Spontaneous cancer and its possible relationship to oxygen metabolism

http://www.wikidata.org/entity/Q36362188

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A perspective on nonmutagenic mechanisms in carcinogenesis Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis Normal oxidative damage to mitochondrial and nuclear DNA is extensive DNA base modifications in chromatin of human cancerous tissues Selenium and vitamin E inhibit radiogenic and chemically induced transformation in vitro via different mechanisms Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase Peto's Paradox: evolution's prescription for cancer prevention Can oxidative DNA damage be used as a biomarker of cancer risk in humans? Problems, resolutions and preliminary results from nutritional supplementation studies.Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine Molecular controls of the oxygenation and redox reactions of hemoglobin Superoxide dismutase (sod-1) null mutants of Neurospora crassa: oxidative stress sensitivity, spontaneous mutation rate and response to mutagens Correlation of individual papilloma latency time with DNA adducts, 8-hydroxy-2'-deoxyguanosine, and the rate of DNA synthesis in the epidermis of mice treated with 7,12-dimethylbenz[alpha]anthracene Thymine glycol and thymidine glycol in human and rat urine: a possible assay for oxidative DNA damage.Acute exercise increases resistance to oxidative stress in young but not older adults.Genetic toxicology: current status of methods of carcinogen identification How does cyanide inhibit superoxide reductase? Insight from synthetic FeIIIN4S model complexes.Oxidative DNA damage: biological significance and methods of analysis.Oxidation of DNA bases by tumor promoter-activated processes.Irradiation-resistance conferred by superoxide dismutase: possible adaptive role of a natural polymorphism in Drosophila melanogaster.Oxidants are a major contributor to aging.Pharmacognostic evaluation of toona ciliata bark.Presidential address. Recent concepts of initiation and promotion in carcinogenesis.Isolation and characterization of methyl viologen-sensitive mutants of Escherichia coli K-12.Active oxygen acts as a promoter of transformation in mouse embryo C3H/10T1/2/C18 fibroblasts.Tandem double CC-->TT mutations are produced by reactive oxygen species.Oxidative stress as the leading cause of acute myocardial infarction in diabetics.Occupational cancer: interaction with life style factors.Molecular studies on coronary artery disease-a review.DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems.Peroxide-producing potential of tissues: inverse correlation with longevity of mammalian species.Carotenoids and retinol: their possible importance in determining longevity of primate species.Biological detection by optical oxygen sensing.The Antioxidant Effect of Exercise: A Systematic Review and Meta-Analysis.Long-term adaptation of the human lung tumor cell line A549 to increasing concentrations of hydrogen peroxide.Ionizing radiation-induced mutagenesis.Dysdifferentiation hypothesis of aging and cancer: a comparison with the membrane hypothesis of aging.Pulmonary carcinogenic effects of ozone.Sequence specific damage of DNA induced by reducing sugars.Free-radical theory of aging. Increasing the functional life span.Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

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Spontaneous cancer and its possible relationship to oxygen metabolism

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Proceedings of the National Academy of Sciences of the United States of America

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Spontaneous cancer and its possible relationship to oxygen metabolism

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Totter JR

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P2860

The biology of oxygen radicals

Breakage of Chromosomes by Oxygen.

MUTAGENIC EFFECTS OF HIGH OXYGEN TENSIONS ON ESCHERICHIA COLI.

Contribution of the environment to cancer incidence: an epidemiologic exercise.

Mutagenic and inactivating DNA alterations.

The effect of iron on the distribution of superoxide and hydroxyl radicals as seen by spin trapping and on the superoxide dismutase assay.

Are physiological oxygen concentrations mutagenic?

Cancer incidence and mortality trends in the United States: 1935-74.

The Effect of Oxygen and of Hydrogen Peroxide on the Action of a Specific Gene and on Tumor Induction in Drosophila Melanogaster.

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