Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells
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Signaling in T cells - is anything the m(a)TOR with the picture(s)?Single-cell technologies are revolutionizing the approach to rare cellsCCR4 promotes medullary entry and thymocyte-dendritic cell interactions required for central tolerance.Fourth Generation of Next-Generation Sequencing Technologies: Promise and ConsequencesCellular and molecular regulation of innate inflammatory responsesCentral tolerance to self revealed by the autoimmune regulator.MHC class I-associated peptides derive from selective regions of the human genome.Power analysis of single-cell RNA-sequencing experiments.Single-cell RNA sequencing to explore immune cell heterogeneity.EBI2 contributes to the induction of thymic central tolerance in mice by promoting rapid motility of medullary thymocytes.Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity.Single-Cell RNA-Sequencing: Assessment of Differential Expression Analysis Methods.AIRE expands: new roles in immune tolerance and beyond.Autoimmune regulator and self-tolerance - molecular and clinical aspects.Development of T-cell tolerance utilizes both cell-autonomous and cooperative presentation of self-antigen.Generation of diversity in thymic epithelial cells.IL-2 and IL-15 dependent thymic development of Foxp3-expressing regulatory T lymphocytes.Extensive RNA editing and splicing increase immune self-representation diversity in medullary thymic epithelial cells.Thymus medulla under construction: Time and space oddities.The transcriptional regulator Aire binds to and activates super-enhancers.Revisiting the Road Map of Medullary Thymic Epithelial Cell Differentiation.Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen.Single-cell RNA-sequencing resolves self-antigen expression during mTEC development.Update on Aire and thymic negative selection.Rapid chromatin repression by Aire provides precise control of immune tolerance.Twenty Years of AIRE.Switching on the Aire conditioner.Autoimmune-Mediated Thymic Atrophy Is Accelerated but Reversible in RelB-Deficient Mice.Comprehensively Profiling the Chromatin Architecture of Tissue Restricted Antigen Expression in Thymic Epithelial Cells Over Development
P2860
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P2860
Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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name
Single-cell transcriptome anal ...... ullary thymic epithelial cells
@ast
Single-cell transcriptome anal ...... ullary thymic epithelial cells
@en
type
label
Single-cell transcriptome anal ...... ullary thymic epithelial cells
@ast
Single-cell transcriptome anal ...... ullary thymic epithelial cells
@en
prefLabel
Single-cell transcriptome anal ...... ullary thymic epithelial cells
@ast
Single-cell transcriptome anal ...... ullary thymic epithelial cells
@en
P2093
P2860
P50
P356
P1433
P1476
Single-cell transcriptome anal ...... ullary thymic epithelial cells
@en
P2093
Bruno Kyewski
Lars M Steinmetz
Michelle Nguyen
Philip Brennecke
Rita Küchler
Sheena Pinto
P2860
P304
P356
10.1038/NI.3246
P407
P577
2015-08-03T00:00:00Z