Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.
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CD44 cell adhesion moleculesCell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesisConcise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic TargetCa(2+)/calmodulin-dependent protein kinase mediates the phosphorylation of CD44 required for cell migration on hyaluronanThe NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44Non-small cell lung cancer cyclooxygenase-2-dependent invasion is mediated by CD44Mycobacteria exploit host hyaluronan for efficient extracellular replicationExpression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathwayFunctional hierarchy of simultaneously expressed adhesion receptors: integrin alpha2beta1 but not CD44 mediates MV3 melanoma cell migration and matrix reorganization within three-dimensional hyaluronan-containing collagen matricesDevelopment of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking.Anti-metastatic effect of a non-anticoagulant low-molecular-weight heparin versus the standard low-molecular-weight heparin, enoxaparinActions of heparin that may affect the malignant process.Prognostic value of serum CD44, intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 levels in patients with indolent non-Hodgkin lymphomas.Stromal hyaluronan interaction with epithelial CD44 variants promotes prostate cancer invasiveness by augmenting expression and function of hepatocyte growth factor and androgen receptorRecent advances on skin-resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies.Localized doxorubicin chemotherapy with a biopolymeric nanocarrier improves survival and reduces toxicity in xenografts of human breast cancer.Proteome analysis of multidrug-resistant, breast cancer-derived microparticles.Hyaluronan binding motifs of USP17 and SDS3 exhibit anti-tumor activity.Spatio-temporal patterns of pancreatic cancer cells expressing CD44 isoforms on supported membranes displaying hyaluronic acid oligomers arrays.Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesionA novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cellsAutocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasionTumor-targeted hyaluronan nanoliposomes increase the antitumor activity of liposomal Doxorubicin in syngeneic and human xenograft mouse tumor models.Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion.CD44 and HCELL: preventing hematogenous metastasis at step 1.Hyaluronan fragments promote inflammation by down-regulating the anti-inflammatory A2a receptor.Hyaluronan production in human rheumatoid fibroblastic synovial lining cells is increased by interleukin 1 beta but inhibited by transforming growth factor beta 1.Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival.Perturbation of hyaluronan interactions by soluble CD44 inhibits growth of murine mammary carcinoma cells in ascites.Perturbation of hyaluronan interactions inhibits malignant properties of glioma cellsStructural variability of CD44v molecules and reliability of immunodetection of CD44 isoforms using mAbs specific for CD44 variant exon products.Increased hyaluronan at sites of attachment to mesentery by CD44-positive mouse ovarian and breast tumor cells.CD44 and beta1 integrin mediate ovarian carcinoma cell adhesion to peritoneal mesothelial cells.Focal loss of CD44 variant protein expression is related to recurrence in superficial bladder carcinomaReduced level of CD44 and hyaluronan associated with unfavorable prognosis in clinical stage I cutaneous melanoma.Novel biomarkers and therapeutic targets for optimizing the therapeutic management of melanomasA simple method for the synthesis of hyaluronic acid coated magnetic nanoparticles for highly efficient cell labelling and in vivo imaging.Activation of CD44, a receptor for extracellular matrix components, protects chronic lymphocytic leukemia cells from spontaneous and drug induced apoptosis through MCL-1Hyaluronan: a critical component of epithelial-mesenchymal and epithelial-carcinoma transitions.The interaction of versican with its binding partners.
P2860
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P2860
Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
Interaction between CD44 and h ...... gulation of tumor development.
@ast
Interaction between CD44 and h ...... gulation of tumor development.
@en
type
label
Interaction between CD44 and h ...... gulation of tumor development.
@ast
Interaction between CD44 and h ...... gulation of tumor development.
@en
prefLabel
Interaction between CD44 and h ...... gulation of tumor development.
@ast
Interaction between CD44 and h ...... gulation of tumor development.
@en
P2093
P2860
P356
P1476
Interaction between CD44 and h ...... egulation of tumor development
@en
P2093
P2860
P356
10.1084/JEM.180.1.53
P407
P577
1994-07-01T00:00:00Z