Vaccination against Lyme disease caused by diverse Borrelia burgdorferi - Wikidata - wikimedia - TriplyDB

Vaccination against Lyme disease caused by diverse Borrelia burgdorferi

Vaccination against Lyme disease caused by diverse Borrelia burgdorferi

http://www.wikidata.org/entity/Q36364234

about

Molecular typing of Borrelia burgdorferi sensu lato: taxonomic, epidemiological, and clinical implications Access of antibody or trypsin to an integral outer membrane protein (P66) of Borrelia burgdorferi is hindered by Osp lipoproteins.Design and development of a novel vaccine for protection against Lyme borreliosis.Detection of anti-Borrelia burgdorferi antibody responses with the borreliacidal antibody test, indirect fluorescent-antibody assay performed by flow cytometry, and western immunoblotting Selection of variant Borrelia burgdorferi isolates from mice immunized with outer surface protein A or B.A 55-kilodalton antigen encoded by a gene on a Borrelia burgdorferi 49-kilobase plasmid is recognized by antibodies in sera from patients with Lyme disease.Outer surface protein C (OspC), but not P39, is a protective immunogen against a tick-transmitted Borrelia burgdorferi challenge: evidence for a conformational protective epitope in OspC Resistance to tick-borne spirochete challenge induced by Borrelia burgdorferi strains that differ in expression of outer surface proteins.Reactivity with a specific epitope of outer surface protein A predicts protection from infection with the Lyme disease spirochete, Borrelia burgdorferi Feeding of ticks on animals for transmission and xenodiagnosis in Lyme disease research.An ecological approach to preventing human infection: vaccinating wild mouse reservoirs intervenes in the Lyme disease cycle The novel Lyme borreliosis vaccine VLA15 shows broad protection against Borrelia species expressing six different OspA serotypes.Structural Investigation ofBorrelia burgdorferiOspB, a BactericidalFab Target

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Vaccination against Lyme disease caused by diverse Borrelia burgdorferi

http://www.wikidata.org/entity/Q36364234

description

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Vaccination against Lyme disease caused by diverse Borrelia burgdorferi

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Vaccination against Lyme disease caused by diverse Borrelia burgdorferi

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Vaccination against Lyme disease caused by diverse Borrelia burgdorferi

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Vaccination against Lyme disease caused by diverse Borrelia burgdorferi

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Vaccination against Lyme disease caused by diverse Borrelia burgdorferi

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Vaccination against Lyme disease caused by diverse Borrelia burgdorferi

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Vaccination against Lyme disease caused by diverse Borrelia burgdorferi

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A Spielman

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E Fikrig

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F R Matuschka

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F S Kantor

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M Chen

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R A Flavell

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R B Kimsey

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R Wallich

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S R Telford

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S W Barthold

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P2860

Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis.

Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice.

An OspB mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo.

Seroprotective groups among isolates of Borrelia burgdorferi.

Variations in the ospB gene of Borrelia burgdorferi result in differences in monoclonal antibody reactivity and in production of escape variants

Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization

Evasion of protective immunity by Borrelia burgdorferi by truncation of outer surface protein B.

Protection against antigenically variable Borrelia burgdorferi conferred by recombinant vaccines.

Borrelia burgdorferi is clonal: implications for taxonomy and vaccine development.

An OspA serotyping system for Borrelia burgdorferi based on reactivity with monoclonal antibodies and OspA sequence analysis.

P304

215-221

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1

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7807004

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Borrelia burgdorferi

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2191810

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