Blocking the transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in SCID mice.
about
Human TFDP3, a novel DP protein, inhibits DNA binding and transactivation by E2FARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF.Adenoviral-E2F-1 radiosensitizes p53wild-type and p53null human prostate cancer cells.Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cellsLoss of E2F1 Extends Survival and Accelerates Oral Tumor Growth in HPV-Positive MiceOverexpression of stathmin in breast carcinomas points out to highly proliferative tumours.Expression of E2F-1 and E2F-4 is reduced in primary and metastatic breast carcinomas.Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p53Facilitation of adenoviral wild-type p53-induced apoptotic cell death by overexpression of p33(ING1) in T.Tn human esophageal carcinoma cells.High incidence of thymic epithelial tumors in E2F2 transgenic mice.
P2860
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P2860
Blocking the transcription factor E2F/DP by dominant-negative mutants in a normal breast epithelial cell line efficiently inhibits apoptosis and induces tumor growth in SCID mice.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Blocking the transcription fac ...... ces tumor growth in SCID mice.
@ast
Blocking the transcription fac ...... ces tumor growth in SCID mice.
@en
type
label
Blocking the transcription fac ...... ces tumor growth in SCID mice.
@ast
Blocking the transcription fac ...... ces tumor growth in SCID mice.
@en
prefLabel
Blocking the transcription fac ...... ces tumor growth in SCID mice.
@ast
Blocking the transcription fac ...... ces tumor growth in SCID mice.
@en
P2093
P2860
P356
P1476
Blocking the transcription fac ...... ces tumor growth in SCID mice.
@en
P2093
Grinstein E
P2860
P304
P356
10.1084/JEM.183.3.1205
P407
P577
1996-03-01T00:00:00Z