Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4) - Wikidata - wikimedia - TriplyDB

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

http://www.wikidata.org/entity/Q36367812

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MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4 ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells Role of MD-2 in TLR2- and TLR4-mediated recognition of Gram-negative and Gram-positive bacteria and activation of chemokine genes Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression.Innate immune responses in peptidoglycan recognition protein L-deficient mice Lipopolysaccharide endotoxins MD-2 is necessary for the toll-like receptor 4 protein to undergo glycosylation essential for its translocation to the cell surface Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling Bench-to-bedside review: Toll-like receptors and their role in septic shock.TLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxins IL-12 Production Induced by Agaricus blazei Fraction H (ABH) Involves Toll-like Receptor (TLR)The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation Human Coinfection with Borrelia burgdorferi and Babesia microti in the United States Toll-like receptors in the host defense against Pseudomonas aeruginosa respiratory infection and cystic fibrosis Postulates for validating TLR4 agonists Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients Location, location, location: is membrane partitioning everything when it comes to innate immune activation?Role of TLR4 rs4986790A>G and rs4986791C>T Polymorphisms in the Risk of Inflammatory Bowel Disease International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease Activation of interleukin-1 receptor-associated kinase by gram-negative flagellin Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4 Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol Suppression of hepcidin expression and iron overload mediate Salmonella susceptibility in ankyrin 1 ENU-induced mutant Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors Local secretion of urocortin 1 promotes microvascular permeability during lipopolysaccharide-induced inflammation Proteomic identification of macrophage migration-inhibitory factor upon exposure to TiO2 particles Polyunsaturated fatty acid supplementation alters proinflammatory gene expression and reduces the incidence of necrotizing enterocolitis in a neonatal rat model Ketamine suppresses intestinal TLR4 expression and NF-kappaB activity in lipopolysaccharide-treated rats Cloning of porcine NRAMP1 and its induction by lipopolysaccharide, tumor necrosis factor alpha, and interleukin-1beta: role of CD14 and mitogen-activated protein kinases Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. Delineation of a new class of IL-1R-related proteins based on signaling Specific messenger RNA expression for signal transduction molecules by lipopolysaccharide in intestinal macrophages Preexposure of murine macrophages to CpG oligonucleotide results in a biphasic tumor necrosis factor alpha response to subsequent lipopolysaccharide challenge.A mouse model of lethal synergism between influenza virus and Haemophilus influenzae.Viral infection, inflammation and schizophrenia TLR4-dependent lipopolysaccharide-induced shedding of tumor necrosis factor receptors in mouse bone marrow granulocytes.

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Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

http://www.wikidata.org/entity/Q36367812

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1999年學術文章

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name

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

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Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

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type

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Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

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Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

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prefLabel

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

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Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

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Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

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G Leveque

http://www.w3.org/2001/XMLSchema#string

K J Moore

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L Larivière

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P Gros

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S Clermont

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S T Qureshi

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Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine

Genetic and Physical Mapping of theLpsLocus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region

A family of human receptors structurally related to Drosophila Toll

Identification of a novel human zinc finger protein that specifically interacts with the activation domain of lentiviral Tat proteins

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

Assignment of the human gene for pregnancy-associated plasma protein A (PAPPA) to 9q33.1 by fluorescence in situ hybridization to mitotic and meiotic chromosomes

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats

Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg

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