Candidate microbicides block HIV-1 infection of human immature Langerhans cells within epithelial tissue explants
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Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activityLangerin is a natural barrier to HIV-1 transmission by Langerhans cellsA series of diaryltriazines and diarylpyrimidines are highly potent nonnucleoside reverse transcriptase inhibitors with possible applications as microbicidesPotent antiviral synergy between monoclonal antibody and small-molecule CCR5 inhibitors of human immunodeficiency virus type 1Anti-HIV-1 activity of cellulose acetate phthalate: synergy with soluble CD4 and induction of "dead-end" gp41 six-helix bundles.Anti-HIV-1 activity of anionic polymers: a comparative study of candidate microbicides.Water dispersible microbicidal cellulose acetate phthalate filmCellulose acetate phthalate, a common pharmaceutical excipient, inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120Animal and human mucosal tissue models to study HIV biomedical interventions: can we predict success?Dendritic Cells in HIV-1 and HCV Infection: Can They Help Win the Battle?Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cellsBottlenecks in HIV-1 transmission: insights from the study of founder virusesMicrobicides and other topical agents in the prevention of HIV and sexually transmitted infections.Memory CD4(+) T cells are the earliest detectable human immunodeficiency virus type 1 (HIV-1)-infected cells in the female genital mucosal tissue during HIV-1 transmission in an organ culture system.Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytesHIV-1 efficient entry in inner foreskin is mediated by elevated CCL5/RANTES that recruits T cells and fuels conjugate formation with Langerhans cells.Sugar-binding proteins potently inhibit dendritic cell human immunodeficiency virus type 1 (HIV-1) infection and dendritic-cell-directed HIV-1 transfer.Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis.Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C.Human immature Langerhans cells restrict CXCR4-using HIV-1 transmission.Use of human mucosal tissue to study HIV-1 pathogenesis and evaluate HIV-1 prevention modalities.Targeted delivery of PSC-RANTES for HIV-1 prevention using biodegradable nanoparticles.Dendritic-cell interactions with HIV: infection and viral dissemination.Early HIV-1 target cells in human vaginal and ectocervical mucosaFormulation development of retrocyclin 1 analog RC-101 as an anti-HIV vaginal microbicide product.Immunologic, virologic, and pharmacologic characterization of the female upper genital tract in HIV-infected women.PSC-RANTES blocks R5 human immunodeficiency virus infection of Langerhans cells isolated from individuals with a variety of CCR5 diplotypes.HIV-1 infection of human penile explant tissue and protection by candidate microbicides.R5 HIV productively infects Langerhans cells, and infection levels are regulated by compound CCR5 polymorphismsDevelopment of a new methodology for screening of human immunodeficiency virus type 1 microbicides based on real-time PCR quantificationPreferential infection of dendritic cells during human immunodeficiency virus type 1 infection of blood leukocytes.Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1.Toward an understanding of the interaction between filarial parasites and host antigen-presenting cells.Pattern Recognition Receptors in HIV Transmission.APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infectionIdentification of an arsenic-sensitive block to primate lentiviral infection of human dendritic cells.Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells.TNF-alpha and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vivoMucosal immune responses in the genital tract of HIV-1-exposed uninfected women.
P2860
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P2860
Candidate microbicides block HIV-1 infection of human immature Langerhans cells within epithelial tissue explants
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
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name
Candidate microbicides block H ...... hin epithelial tissue explants
@ast
Candidate microbicides block H ...... hin epithelial tissue explants
@en
type
label
Candidate microbicides block H ...... hin epithelial tissue explants
@ast
Candidate microbicides block H ...... hin epithelial tissue explants
@en
prefLabel
Candidate microbicides block H ...... hin epithelial tissue explants
@ast
Candidate microbicides block H ...... hin epithelial tissue explants
@en
P2093
P2860
P356
P1476
Candidate microbicides block H ...... hin epithelial tissue explants
@en
P2093
A Blauvelt
A R Neurath
D L Borris
E A Aquilino
J M Orenstein
L B Margolis
R E Offord
S Glushakova
T Kawamura
P2860
P304
P356
10.1084/JEM.192.10.1491
P407
P577
2000-11-01T00:00:00Z