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Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYNDiscovery of Novel Irreversible Inhibitors of Interleukin (IL)-2-inducible Tyrosine Kinase (Itk) by Targeting Cysteine 442 in the ATP PocketTranscriptional regulation of kinases downstream of the T cell receptor: another immunomodulatory mechanism of glucocorticoids.The impact of DMARD and anti-TNF therapy on functional characterization of short-term T-cell activation in patients with rheumatoid arthritis--a follow-up study.Increased p300 expression inhibits glucocorticoid receptor-T-cell receptor antagonism but does not affect thymocyte positive selectionIncreased membrane cholesterol in lymphocytes diverts T-cells toward an inflammatory responseThe roles of membrane microdomains (rafts) in T cell activation.CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1.Reduced telomerase activity in human T lymphocytes exposed to cortisolDexamethasone augments CXCR4-mediated signaling in resting human T cells via the activation of the Src kinase LckApoptosis and autophagy: decoding calcium signals that mediate life or death.Protein kinase networks regulating glucocorticoid-induced apoptosis of hematopoietic cancer cells: fundamental aspects and practical considerations.Coming full circle: 70 years of chronic lymphocytic leukemia cell redistribution, from glucocorticoids to inhibitors of B-cell receptor signalingEffect of Immunosuppressive Drugs on Humoral Allosensitization after Kidney Transplant.Glucocorticoids downregulate Fyn and inhibit IP(3)-mediated calcium signaling to promote autophagy in T lymphocytes.Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia.Factors affecting reconstitution of the T cell compartment in allogeneic haematopoietic cell transplant recipients.Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4+ T cells.Glucocorticoid-mediated inhibition of Lck modulates the pattern of T cell receptor-induced calcium signals by down-regulating inositol 1,4,5-trisphosphate receptors.Comparative analysis of assays for detection of cell-mediated immunity toward cytomegalovirus and M. tuberculosis in samples from deceased organ donors.Low levels of NF-κB/p65 mark anergic CD4+ T cells and correlate with disease severity in sarcoidosis.LAT displacement from lipid rafts as a molecular mechanism for the inhibition of T cell signaling by polyunsaturated fatty acids.Amelioration of experimental colitis after short-term therapy with glucocorticoid and its relationship to the induction of different regulatory markers.Glucocorticoids Suppress CCR9-Mediated Chemotaxis, Calcium Flux, and Adhesion to MAdCAM-1 in Human T Cells.L-plastin phosphorylation: a novel target for the immunosuppressive drug dexamethasone in primary human T cells.Glucocorticoids, Sex Hormones, and Immunity.
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Glucocorticoids attenuate T cell receptor signaling.
@ast
Glucocorticoids attenuate T cell receptor signaling.
@en
type
label
Glucocorticoids attenuate T cell receptor signaling.
@ast
Glucocorticoids attenuate T cell receptor signaling.
@en
prefLabel
Glucocorticoids attenuate T cell receptor signaling.
@ast
Glucocorticoids attenuate T cell receptor signaling.
@en
P2093
P2860
P356
P1476
Glucocorticoids attenuate T cell receptor signaling.
@en
P2093
D Kioussis
F Van Laethem
P2860
P304
P356
10.1084/JEM.193.7.803
P407
P577
2001-04-01T00:00:00Z