Neonatally induced inactivation of the vascular cell adhesion molecule 1 gene impairs B cell localization and T cell-dependent humoral immune response
about
Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes.B-cell receptor signalling and its crosstalk with other pathways in normal and malignant cellsInhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseasesVCAM-1 is critical in atherosclerosis.Leukocyte adhesion molecules in animal models of inflammatory bowel diseaseB-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1Cannabinoid receptor 2 mediates the retention of immature B cells in bone marrow sinusoidsDistinct changes in adult lymphopoiesis in Rag2-/- mice fully reconstituted by alpha4-deficient adult bone marrow cells.CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrowDown regulation of genes involved in T cell polarity and motility during the induction of heart allograft tolerance by allochimeric MHC I.An essential role of the cytoplasmic tail of CXCR4 in G-protein signaling and organogenesis.Shp1 signalling is required to establish the long-lived bone marrow plasma cell pool.Lymphocyte homing to bronchus-associated lymphoid tissue (BALT) is mediated by L-selectin/PNAd, alpha4beta1 integrin/VCAM-1, and LFA-1 adhesion pathwaysWnt-related molecules and signaling pathway equilibrium in hematopoiesis.The tetraspanin CD37 orchestrates the α(4)β(1) integrin-Akt signaling axis and supports long-lived plasma cell survival.Deletion of alpha4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing.VCAM-1 signals during lymphocyte migration: role of reactive oxygen speciesHoming of antibody secreting cells.Sustained alterations in biodistribution of stem/progenitor cells in Tie2Cre+ alpha4(f/f) mice are hematopoietic cell autonomous.VCAM-1 expression in adult hematopoietic and nonhematopoietic cells is controlled by tissue-inductive signals and reflects their developmental origin.Functional knock down of VCAM1 in mice mediated by endoplasmatic reticulum retained intrabodiesGranulocytic adhesive interactions and their role in sickle cell vaso-occlusion.Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrowA coordinated change in chemokine responsiveness guides plasma cell movementsShort-lived and long-lived bone marrow plasma cells are derived from a novel precursor population.Sustained activation of cell adhesion is a differentially regulated process in B lymphopoiesisNatalizumab and progressive multifocal leukoencephalopathy: migrating towards safe adhesion molecule therapy in multiple sclerosis.Improved monitoring of clinical response in Systemic Lupus Erythematosus by longitudinal trend in soluble vascular cell adhesion molecule-1.An initial top-down proteomic analysis of the standard cuprizone mouse model of multiple sclerosisHAX1 deletion impairs BCR internalization and leads to delayed BCR-mediated apoptosis.Lymphotoxin α1β2 expression on B cells is required for follicular dendritic cell activation during the germinal center responseCanonical Wnt pathway signaling suppresses VCAM-1 expression by marrow stromal and hematopoietic cells.Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice.PTH Signaling in Osteoprogenitors Is Essential for B-Lymphocyte Differentiation and Mobilization.Genetic transfer of fusion proteins effectively inhibits VCAM-1-mediated cell adhesion and transmigration via inhibition of cytoskeletal anchorage.The role of the tec kinase Bruton's tyrosine kinase (Btk) in leukocyte recruitment.Mechanisms of pre-B-cell receptor checkpoint control and its oncogenic subversion in acute lymphoblastic leukemia.Adhesion receptors involved in HSC and early-B cell interactions with bone marrow microenvironment.The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes.Accumulation of prelamin A compromises NF-κB-regulated B-lymphopoiesis in a progeria mouse model.
P2860
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P2860
Neonatally induced inactivation of the vascular cell adhesion molecule 1 gene impairs B cell localization and T cell-dependent humoral immune response
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Neonatally induced inactivatio ...... endent humoral immune response
@ast
Neonatally induced inactivatio ...... endent humoral immune response
@en
type
label
Neonatally induced inactivatio ...... endent humoral immune response
@ast
Neonatally induced inactivatio ...... endent humoral immune response
@en
prefLabel
Neonatally induced inactivatio ...... endent humoral immune response
@ast
Neonatally induced inactivatio ...... endent humoral immune response
@en
P2093
P2860
P356
P1476
Neonatally induced inactivatio ...... endent humoral immune response
@en
P2093
P2860
P304
P356
10.1084/JEM.193.6.755
P407
P577
2001-03-01T00:00:00Z