Differential antigen presentation regulates the changing patterns of CD8+ T cell immunodominance in primary and secondary influenza virus infections.
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Cross-competition of CD8+ T cells shapes the immunodominance hierarchy during boost vaccinationApoptotic cells deliver processed antigen to dendritic cells for cross-presentationComplete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchyProtective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation ThresholdStructural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responsesAcute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptidesStrategic Priming with Multiple Antigens can Yield Memory Cell Phenotypes Optimized for Infection with Mycobacterium tuberculosis: A Computational StudyPatterns of predicted T-cell epitopes associated with antigenic drift in influenza H3N2 hemagglutininVaccinia-based influenza vaccine overcomes previously induced immunodominance hierarchy for heterosubtypic protection.Diverse heterologous primary infections radically alter immunodominance hierarchies and clinical outcomes following H7N9 influenza challenge in miceEosinophils Promote Antiviral Immunity in Mice Infected with Influenza A VirusSubsisting H1N1 influenza memory responses are insufficient to protect from pandemic H1N1 influenza challenge in C57BL/6 mice.Antiviral CD8+ T cell effector activities in situ are regulated by target cell typeConsequences of immunodominant epitope deletion for minor influenza virus-specific CD8+-T-cell responses.Dendritic cells maximize the memory CD8 T cell response to infection.Coverage of related pathogenic species by multivalent and cross-protective vaccine design: arenaviruses as a model systemContribution of T cell receptor affinity to overall avidity for virus-specific CD8+ T cell responsesProlonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cells.Rapid recruitment of virus-specific CD8 T cells restructures immunodominance during protective secondary responsesPathogen evolution and the immunological niche.Responses against a subdominant CD8+ T cell epitope protect against immunopathology caused by a dominant epitope.Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection.A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequenciesA novel HLA-B18 restricted CD8+ T cell epitope is efficiently cross-presented by dendritic cells from soluble tumor antigen.Direct interrogation of viral peptides presented by the class I HLA of HIV-infected T cells.Immunodomination during peripheral vaccinia virus infection.Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite.Mucosal vaccination with recombinant adenovirus encoding nucleoprotein provides potent protection against influenza virus infection.Effect of MHC class I diversification on influenza epitope-specific CD8+ T cell precursor frequency and subsequent effector function.Properties of MHC class I presented peptides that enhance immunogenicityContributions of antinucleoprotein IgG to heterosubtypic immunity against influenza virusAge-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice.Virally activated CD8 T cells home to Mycobacterium bovis BCG-induced granulomas but enhance antimycobacterial protection only in immunodeficient mice.OX40 ligand and programmed cell death 1 ligand 2 expression on inflammatory dendritic cells regulates CD4 T cell cytokine production in the lung during viral disease.Stress and the anti-influenza immune response: repeated social defeat augments clonal expansion of CD8(+)T cells during primary influenza A viral infection.Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infectionNaive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominanceMapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirusInduction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasiaPersistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response.
P2860
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P2860
Differential antigen presentation regulates the changing patterns of CD8+ T cell immunodominance in primary and secondary influenza virus infections.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Differential antigen presentat ...... ry influenza virus infections.
@ast
Differential antigen presentat ...... ry influenza virus infections.
@en
type
label
Differential antigen presentat ...... ry influenza virus infections.
@ast
Differential antigen presentat ...... ry influenza virus infections.
@en
prefLabel
Differential antigen presentat ...... ry influenza virus infections.
@ast
Differential antigen presentat ...... ry influenza virus infections.
@en
P2093
P2860
P356
P1476
Differential antigen presentat ...... ry influenza virus infections.
@en
P2093
Alan D Roberts
David L Woodland
Kenneth H Ely
Rachel A Rappolo
Shannon C Miller
Sherry R Crowe
P2860
P304
P356
10.1084/JEM.20022151
P407
P577
2003-07-28T00:00:00Z