JAK/STAT signal transduction: regulators and implication in hematological malignancies.
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Heme controls the regulation of protein tyrosine kinases Jak2 and SrcCytotoxicity of apigenin on leukemia cell lines: implications for prevention and therapyJAK kinase targeting in hematologic malignancies: a sinuous pathway from identification of genetic alterations towards clinical indicationsModulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode DependentThe natural chemopreventive agent sulforaphane inhibits STAT5 activityLactogens protect rodent and human beta cells against glucolipotoxicity-induced cell death through Janus kinase-2 (JAK2)/signal transducer and activator of transcription-5 (STAT5) signallingProtein tyrosine phosphatases in the JAK/STAT pathwayDistinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemiaLeishmania infantum-chagasi activates SHP-1 and reduces NFAT5/TonEBP activity in the mouse kidney inner medulla.Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cellsThe benzoxathiolone LYR-71 down-regulates interferon-gamma-inducible pro-inflammatory genes by uncoupling tyrosine phosphorylation of STAT-1 in macrophagesDynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling.Global methylation and promoter-specific methylation of the P16, SOCS-1, E-cadherin, P73 and SHP-1 genes and their expression in patients with multiple myeloma during active disease and remissionHepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activationAssociation Study of rs3184504 C>T Polymorphism in Patients With Coronary Artery Disease.Prolactin inhibits activity of pyruvate kinase M2 to stimulate cell proliferationInferring relevant control mechanisms for interleukin-12 signaling in naïve CD4+ T cells.Phase I study of a novel oral Janus kinase 2 inhibitor, SB1518, in patients with relapsed lymphoma: evidence of clinical and biologic activity in multiple lymphoma subtypes.Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lungDrugs and their molecular targets: an updated overview.The synthetic α-bromo-2',3,4,4'-tetramethoxychalcone (α-Br-TMC) inhibits the JAK/STAT signaling pathway.NF-κB and STAT3 - key players in liver inflammation and cancerThe two faces of Janus kinases and their respective STATs in mammary gland development and cancerIntegrated molecular profiling of SOD2 expression in multiple myelomaMicroRNA-204 targets JAK2 in breast cancer and induces cell apoptosis through the STAT3/BCl-2/survivin pathwayElevated serum IL-10 levels in diffuse large B-cell lymphoma: a mechanism of aberrant JAK2 activation.Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling.Signal transducer and activator of transcription STAT5 is recruited to c-Myc super-enhancer.The Chemopreventive Phytochemical Moringin Isolated from Moringa oleifera Seeds Inhibits JAK/STAT Signaling.Protein tyrosine phosphatase SHP-1 sensitizes EGFR/HER-2 positive breast cancer cells to trastuzumab through modulating phosphorylation of EGFR and HER-2.Constitutive Activation of Interleukin-13/STAT6 Contributes to Kaposi's Sarcoma-Associated Herpesvirus-Related Primary Effusion Lymphoma Cell Proliferation and Survival.Altered expression of cytokine signaling pathway genes in peripheral blood cells of alcohol dependent subjects: preliminary findings.JAK-STAT pathway in carcinogenesis: is it relevant to cholangiocarcinoma progression?Prognostic significance of phosphorylated signal transducer and activator of transcription 3 and suppressor of cytokine signaling 3 expression in hepatocellular carcinoma.Epigenetic regulation of signal transducer and activator of transcription 3 in acute myeloid leukemiaAbnormal repression of SHP-1, SHP-2 and SOCS-1 transcription sustains the activation of the JAK/STAT3 pathway and the progression of the disease in multiple myeloma.Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapiesProtein therapeutics: new applications for pharmacogenetics.The role of Janus kinases in haemopoiesis and haematological malignancy.Point mutations of protein kinases and individualised cancer therapy.
P2860
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P2860
JAK/STAT signal transduction: regulators and implication in hematological malignancies.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
JAK/STAT signal transduction: regulators and implication in hematological malignancies.
@ast
JAK/STAT signal transduction: regulators and implication in hematological malignancies.
@en
type
label
JAK/STAT signal transduction: regulators and implication in hematological malignancies.
@ast
JAK/STAT signal transduction: regulators and implication in hematological malignancies.
@en
prefLabel
JAK/STAT signal transduction: regulators and implication in hematological malignancies.
@ast
JAK/STAT signal transduction: regulators and implication in hematological malignancies.
@en
P1476
JAK/STAT signal transduction: regulators and implication in hematological malignancies.
@en
P2093
Josiane Pierre
Lyne Valentino
P304
P356
10.1016/J.BCP.2005.12.017
P407
P577
2006-01-19T00:00:00Z