Macrophage and retinal pigment epithelium phagocytosis: apoptotic cells and photoreceptors compete for alphavbeta3 and alphavbeta5 integrins, and protein kinase C regulates alphavbeta5 binding and cytoskeletal linkage.
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Functional roles of bestrophins in ocular epitheliaPhosphatidylserine receptors: enhancers of enveloped virus entry and infectionRegulation of phagocytosis by Rho GTPasesFocal adhesion kinase signaling promotes phagocytosis of integrin-bound photoreceptorsTetraspanin CD81 is required for the alpha v beta5-integrin-dependent particle-binding step of RPE phagocytosisIntegrin αVβ5-mediated Removal of Apoptotic Cell Debris by the Eye Lens and Its Inhibition by UV Light Exposure.Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degenerationPhagocytosis of human retinal pigment epithelial cells: evidence of a diurnal rhythm, involvement of the cytoskeleton and interference of antiviral drugs.Changes in retinal pigment epithelium related to cigarette smoke: possible relevance to smoking as a risk factor for age-related macular degeneration.Increased density of retinal pigment epithelium in cd81-/- miceThe lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium.Understanding photoreceptor outer segment phagocytosis: use and utility of RPE cells in culture.Regulation of phagocytosis by TAM receptors and their ligands.Rho GTPase signalling pathways in the morphological changes associated with apoptosis.Cleavage of Mer tyrosine kinase (MerTK) from the cell surface contributes to the regulation of retinal phagocytosis.Large-scale purification of porcine or bovine photoreceptor outer segments for phagocytosis assays on retinal pigment epithelial cells.Novel role for alphavbeta5-integrin in retinal adhesion and its diurnal peak.Lack of alphavbeta5 integrin receptor or its ligand MFG-E8: distinct effects on retinal function.Microglia use multiple mechanisms to mediate interactions with vitronectin; non-essential roles for the highly-expressed αvβ3 and αvβ5 integrinsAccumulation and autofluorescence of phagocytized rod outer segment material in macrophages and microglial cellsClearance of apoptotic photoreceptors: elimination of apoptotic debris into the subretinal space and macrophage-mediated phagocytosis via phosphatidylserine receptor and integrin alphavbeta3Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinaseRetinal compensatory changes after light damage in albino miceEssential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis.Age-related maculopathy susceptibility 2 participates in the phagocytosis functions of the retinal pigment epithelium.Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina.Differential roles of CD36 and alphavbeta5 integrin in photoreceptor phagocytosis by the retinal pigment epitheliumLoss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin.Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrinVitronectin inhibits efferocytosis through interactions with apoptotic cells as well as with macrophagesRegulation of Phagolysosomal Digestion by Caveolin-1 of the Retinal Pigment Epithelium Is Essential for Vision.The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cellsNoncanonical autophagy promotes the visual cycleIndependent roles of methionine sulfoxide reductase A in mitochondrial ATP synthesis and as antioxidant in retinal pigment epithelial cells.Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences.The epithelial integrin alphavbeta6 is a receptor for foot-and-mouth disease virus.The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration.αvβ5 integrin-dependent diurnal phagocytosis of shed photoreceptor outer segments by RPE cells is independent of the integrin coreceptor transglutaminase-2.Expression of the integrin coreceptor transglutaminase-2 in the RPE in vivo and in culturePI 3-kinase independent role for AKT in F-actin regulation during outer segment phagocytosis by RPE cells.
P2860
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P2860
Macrophage and retinal pigment epithelium phagocytosis: apoptotic cells and photoreceptors compete for alphavbeta3 and alphavbeta5 integrins, and protein kinase C regulates alphavbeta5 binding and cytoskeletal linkage.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Macrophage and retinal pigment ...... ding and cytoskeletal linkage.
@ast
Macrophage and retinal pigment ...... ding and cytoskeletal linkage.
@en
type
label
Macrophage and retinal pigment ...... ding and cytoskeletal linkage.
@ast
Macrophage and retinal pigment ...... ding and cytoskeletal linkage.
@en
prefLabel
Macrophage and retinal pigment ...... ding and cytoskeletal linkage.
@ast
Macrophage and retinal pigment ...... ding and cytoskeletal linkage.
@en
P2860
P921
P356
P1476
Macrophage and retinal pigment ...... ding and cytoskeletal linkage.
@en
P2093
E Rodriguez-Boulan
S C Finnemann
P2860
P304
P356
10.1084/JEM.190.6.861
P407
P577
1999-09-01T00:00:00Z