Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma. - Wikidata - wikimedia - TriplyDB

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma.

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma.

http://www.wikidata.org/entity/Q36375732

about

Hodgkin's disease and the Epstein-Barr virus.Occurrence of minimal change nephrotic syndrome in classical Hodgkin lymphoma is closely related to the induction of c-mip in Hodgkin-Reed Sternberg cells and podocytes Unexpected functions of nuclear factor-κB during germinal center B-cell development: implications for lymphomagenesis Role of immune escape mechanisms in Hodgkin's lymphoma development and progression: a whole new world with therapeutic implications Lessons from mathematically modeling the NF-κB pathway.Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas The c-Rel transcription factor and B-cell proliferation: a deal with the devil Targeting NF-kappaB in hematologic malignancies Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity TP53 gene mutations in Hodgkin lymphoma are infrequent and not associated with absence of Epstein-Barr virus.Bystander cells and prognosis in Hodgkin lymphoma. Review based on a doctoral thesis.Single agent bortezomib in the treatment of relapsed and refractory Hodgkin lymphoma: cancer and leukemia Group B protocol 50206.TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma.Hodgkin lymphoma: an update on its biology with new insights into classification.The molecular and cellular origins of Hodgkin's disease.KLF6 depletion promotes NF-κB signaling in glioblastoma.Oncogenic activation of NF-kappaB.Advances in the pathophysiology and treatment of relapsed/refractory Hodgkin's lymphoma with an emphasis on targeted therapies and transplantation strategies Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies.Lymphoid malignancies: the dark side of B-cell differentiation.Epstein-Barr virus and oncogenesis: from latent genes to tumours.Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment.Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells.Vitamin D3 receptor is highly expressed in Hodgkin's lymphoma Identification of a NFKBIA polymorphism associated with lower NFKBIA protein levels and poor survival outcomes in patients with glioblastoma multiforme.Molecular biology of Hodgkin's and Reed/Sternberg cells in Hodgkin's lymphoma.EBV in Hodgkin Lymphoma.Hodgkin's lymphoma: the pathologist's viewpoint The molecular pathogenesis of Hodgkin lymphoma.Hodgkin lymphoma.NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions.Subclonal evolution of a classical Hodgkin lymphoma from a germinal center B-cell-derived mantle cell lymphoma.Expression and functional relevance of cannabinoid receptor 1 in Hodgkin lymphoma.Nuclear transcription factor-kappaB in Hodgkin's disease.NF-κB and cancer: a paradigm of Yin-Yang.The complex interplay between autophagy and NF-κB signaling pathways in cancer cells Role of molecular studies in the classification of lymphoma.Expression of Interleukin-1 and Interleukin-1 Receptors Type 1 and Type 2 in Hodgkin Lymphoma.Constitutive expression of c-FLIP in Hodgkin and Reed-Sternberg cells.Mechanisms of B-cell lymphoma pathogenesis.

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P2860

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma.

http://www.wikidata.org/entity/Q36375732

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2000 nî lūn-bûn

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年學術文章

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Clonal deleterious mutations i ...... t cells in Hodgkin's lymphoma.

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Clonal deleterious mutations i ...... t cells in Hodgkin's lymphoma.

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Clonal deleterious mutations i ...... t cells in Hodgkin's lymphoma.

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Clonal deleterious mutations i ...... t cells in Hodgkin's lymphoma.

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Clonal deleterious mutations i ...... t cells in Hodgkin's lymphoma.

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Clonal deleterious mutations i ...... t cells in Hodgkin's lymphoma.

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Journal of Experimental Medicine

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Clonal deleterious mutations i ...... t cells in Hodgkin's lymphoma.

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P2093

A Bräuninger

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A Staratschek-Jox

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B Jungnickel

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J Wolf

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M L Hansmann

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T Spieker

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V Diehl

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P2860

Structure of an IkappaBalpha/NF-kappaB complex

The NF-kappa B and I kappa B proteins: new discoveries and insights

The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

Structure and evolution of the human IKBA gene

Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity

Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.

Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci.

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers.

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2

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191

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10637284

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