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Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages

Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages

http://www.wikidata.org/entity/Q36376172

about

Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus Specific dysregulation of IFNγ production by natural killer cells confers susceptibility to viral infection Latent gammaherpesvirus 68 infection induces distinct transcriptional changes in different organs Tonsilar NK cells restrict B cell transformation by the Epstein-Barr virus via IFN-gamma.Murine cytomegalovirus paralyzes macrophages by blocking IFN gamma-induced promoter assembly.Identification of DNA-damage DNA-binding protein 1 as a conditional essential factor for cytomegalovirus replication in interferon-γ-stimulated cells.A gammaherpesvirus cooperates with interferon-alpha/beta-induced IRF2 to halt viral replication, control reactivation, and minimize host lethality.Lack of XBP-1 impedes murine cytomegalovirus gene expression.IFNγ inhibits the cytosolic replication of Shigella flexneri via the cytoplasmic RNA sensor RIG-I.Post-genomic virology: the impact of bioinformatics, microarrays and proteomics on investigating host and pathogen interactions.Searching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes.CD8 T cells control cytomegalovirus latency by epitope-specific sensing of transcriptional reactivation Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-γ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral state.Coordinate regulation of DNA damage and type I interferon responses imposes an antiviral state that attenuates mouse gammaherpesvirus type 68 replication in primary macrophages.Cytomegalovirus impairs antiviral CD8+ T cell immunity by recruiting inflammatory monocytes.Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta.Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages.Gamma interferon blocks gammaherpesvirus reactivation from latency in a cell type-specific manner.Noncytotoxic functions of NK cells: direct pathogen restriction and assistance to adaptive immunity.Natural killer cells in immunodefense against infective agents.Interplay between CMVs and interferon signaling: implications for pathogenesis and therapeutic intervention.Preactivation of the interferon signalling in liver is correlated with nonresponse to interferon alpha therapy in patients chronically infected with hepatitis B virus.Immune control of the number and reactivation phenotype of cells latently infected with a gammaherpesvirus.Effective inhibition of K(b)- and D(b)-restricted antigen presentation in primary macrophages by murine cytomegalovirus.Murine cytomegalovirus infection inhibits tumor necrosis factor alpha responses in primary macrophages.Natural killer cells utilize both perforin and gamma interferon to regulate murine cytomegalovirus infection in the spleen and liver.Coimmunisation with type I IFN genes enhances protective immunity against cytomegalovirus and myocarditis in gB DNA-vaccinated mice.Type I interferon gene therapy protects against cytomegalovirus-induced myocarditis.Gamma-interferon exerts a critical early restriction on replication and dissemination of yellow fever virus vaccine strain 17D-204.Murine cytomegalovirus degrades MHC class II to colonize the salivary glands.Immune-regulatory transcriptional responses in multiple organs of Atlantic salmon after tributyltin exposure, alone or in combination with forskolin.Control of primary mouse cytomegalovirus infection in lung nodular inflammatory foci by cooperation of interferon-gamma expressing CD4 and CD8 T cells

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P2860

Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages

http://www.wikidata.org/entity/Q36376172

description

2001 nî lūn-bûn

@nan

2001年の論文

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2001年学术文章

@wuu

2001年学术文章

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2001年学术文章

@zh-hans

2001年学术文章

@zh-my

2001年学术文章

@zh-sg

2001年學術文章

@yue

2001年學術文章

@zh

2001年學術文章

@zh-hant

name

Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages

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Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages

@en

type

label

Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages

@ast

Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages

@en

prefLabel

Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages

@ast

Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages

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P1433

Journal of Experimental Medicine

P1476

Novel cell type-specific antiviral mechanism of interferon gamma action in macrophages

@en

P2093

D L Popkin

http://www.w3.org/2001/XMLSchema#string

H W Virgin

http://www.w3.org/2001/XMLSchema#string

M Connick

http://www.w3.org/2001/XMLSchema#string

R M Presti

http://www.w3.org/2001/XMLSchema#string

S Paetzold

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein

Functional role of type I and type II interferons in antiviral defense

The human interferon-inducible protein, IFI 16, is a repressor of transcription

Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91)

Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

P304

483-496

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scholarly article

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10.1084/JEM.193.4.483

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4

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11181700

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