Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia

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Notch and its oncogenic activity in human malignancies.The Notch inhibitor cowanin accelerates nicastrin degradation.

P2860

Q45743019-55307A56-13BA-4D4C-858D-D3C8341CC2A5 Q52337574-005B2E1E-73DE-42A2-8CF7-D5469A932023

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Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia

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http://www.wikidata.org/entity/Q36376809

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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name

Identification of a novel chal ...... l acute lymphoblastic leukemia

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Identification of a novel chal ...... l acute lymphoblastic leukemia

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Identification of a novel chal ...... l acute lymphoblastic leukemia

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Identification of a novel chal ...... l acute lymphoblastic leukemia

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Identification of a novel chal ...... l acute lymphoblastic leukemia

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Identification of a novel chal ...... l acute lymphoblastic leukemia

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P1476

Identification of a novel chal ...... l acute lymphoblastic leukemia

@en

P2093

Bruno Botta

http://www.w3.org/2001/XMLSchema#string

Claudio Talora

http://www.w3.org/2001/XMLSchema#string

Deborah Quaglio

http://www.w3.org/2001/XMLSchema#string

Fabrizio Simeoni

http://www.w3.org/2001/XMLSchema#string

Francesca Ghirga

http://www.w3.org/2001/XMLSchema#string

Francesca Giulimondi

http://www.w3.org/2001/XMLSchema#string

Isabella Screpanti

http://www.w3.org/2001/XMLSchema#string

Maria Elisa Crestoni

http://www.w3.org/2001/XMLSchema#string

Marisa Fusto

http://www.w3.org/2001/XMLSchema#string

Rocco Palermo

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P2860

Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.

Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies

Signalling downstream of activated mammalian Notch

Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase B (PtpB) inhibitors from natural products

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

Notch-1 regulates transcription of the epidermal growth factor receptor through p53.

Natural products in drug discovery.

Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors.

Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic).

P2888

s41598-017-02316-9

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scholarly article

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10.1038/S41598-017-02316-9

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English

P433

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P478

http://www.w3.org/2001/XMLSchema#string

P50

Giovanna Peruzzi

L Tottone

Nadezhda Zhdanovskaya

Mattia Mori

Cinzia Ingallina

P577

2017-05-19T00:00:00Z

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P6179

1085436840

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28526832

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P932

5438367

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Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia

about

P2860

P2860

Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

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P31

P356

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P433

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P577

P6179

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P932

P356

P1433

P1476

P2093

P2860

P2888

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P31

P356

P407

P433

P478

P50

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P6179

P698

P932