Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.

Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.

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http://www.wikidata.org/entity/Q36377576
Dysregulation of ubiquitin ligases in cancerA C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125Ubiquitin ligase UBE3C promotes melanoma progression by increasing epithelial-mesenchymal transition in melanoma cellsChemotherapy Resistance Mechanisms in Advanced Skin Cancer.A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib.Targeted agents and immunotherapies: optimizing outcomes in melanoma.Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF- β1-SMAD3-ID1 signaling pathway.Hydroxytyrosol, a product from olive oil, reduces colon cancer growth by enhancing epidermal growth factor receptor degradation.Identification and functional analysis of SOX10 phosphorylation sites in melanoma.Growth Hormone Receptor Knockdown Sensitizes Human Melanoma Cells to Chemotherapy by Attenuating Expression of ABC Drug Efflux Pumps.Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies.
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Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.

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http://www.wikidata.org/entity/Q36377576
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2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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name
Downregulation of the Ubiquiti ...... ibitors via JAK1 Deregulation.
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Downregulation of the Ubiquiti ...... ibitors via JAK1 Deregulation.
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type
label
Downregulation of the Ubiquiti ...... ibitors via JAK1 Deregulation.
@ast
Downregulation of the Ubiquiti ...... ibitors via JAK1 Deregulation.
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prefLabel
Downregulation of the Ubiquiti ...... ibitors via JAK1 Deregulation.
@ast
Downregulation of the Ubiquiti ...... ibitors via JAK1 Deregulation.
@en
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Downregulation of the Ubiquiti ...... hibitors via JAK1 Deregulation
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10.1016/J.CELREP.2015.04.049
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