SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex

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Functional role of eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) in NSCLC Cutaneous malignant melanoma and Parkinson disease: Common pathways?MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma.

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SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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SBI-0640756 Attenuates the Gro ...... Translation Initiation Complex

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SBI-0640756 Attenuates the Gro ...... Translation Initiation Complex

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SBI-0640756 Attenuates the Gro ...... Translation Initiation Complex

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SBI-0640756 Attenuates the Gro ...... Translation Initiation Complex

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SBI-0640756 Attenuates the Gro ...... Translation Initiation Complex

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SBI-0640756 Attenuates the Gro ...... Translation Initiation Complex

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Brian James

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Christian A Hassig

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Elisa Barile

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Eric Lau

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Hongwei Yin

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Jian-Liang Li

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Kevin M Brown

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Laura Hulea

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Marcus Bosenberg

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Maurizio Pellecchia

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Regulation of translation initiation in eukaryotes: mechanisms and biological targets

Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11.

Effective inhibition of melanoma by BI-69A11 is mediated by dual targeting of the AKT and NF-κB pathways

Differential Requirements for eIF4E Dose in Normal Development and Cancer

DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs

Targeting the eukaryotic translation initiation factor 4E for cancer therapy.

Synthesis and SAR studies of dual AKT/NF-κB inhibitors against melanoma.

NRAS mutant melanoma: biological behavior and future strategies for therapeutic management.

New strategies in metastatic melanoma: oncogene-defined taxonomy leads to therapeutic advances.

Regulation of mRNA translation by signaling pathways

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5211-5218

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scholarly article

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10.1158/0008-5472.CAN-15-0885

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English

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2015-11-24T00:00:00Z

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4681635

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SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex

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P2860

P2860

SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex

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