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Present and future therapies of hepatitis B: From discovery to cure

Present and future therapies of hepatitis B: From discovery to cure

http://www.wikidata.org/entity/Q36378278

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Review of Laboratory Tests used in Monitoring Hepatitis B Response to Pegylated Interferon and Nucleos(t)ide Analog Therapy Advances and Challenges in Studying Hepatitis B Virus In Vitro Symbiotic chemo- and immuno-therapy for hepatitis B and C viruses A Convenient Truth: Cost of Medications Need Not Be a Barrier to Hepatitis B Treatment Epidemiology of Hepatitis B Virus Infection and Impact of Vaccination on Disease.The Role of cccDNA in HBV Maintenance.Detection of HBV Covalently Closed Circular DNA Hepatitis B virus strains from Rwandan blood donors are genetically similar and form one clade within subgenotype A1.Interferon-inducible ribonuclease ISG20 inhibits hepatitis B virus replication through directly binding to the epsilon stem-loop structure of viral RNA Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus Evolving New Strategies for the Medical Management of Chronic Hepatitis B Virus Infection.Control of Hepatitis B Virus by Cytokines Prospects and progress of DNA vaccines for treating hepatitis B.Sodium taurocholate cotransporting polypeptide is the limiting host factor of hepatitis B virus infection in macaque and pig hepatocytes.New therapies for chronic hepatitis B.Hepatitis B Reactivation Associated With Immune Suppressive and Biological Modifier Therapies: Current Concepts, Management Strategies, and Future Directions.Establishment of an inducible HBV stable cell line that expresses cccDNA-dependent epitope-tagged HBeAg for screening of cccDNA modulators.Hepatitis B virus inhibits insulin receptor signaling and impairs liver regeneration via intracellular retention of the insulin receptor.Experimental models of hepatitis B and C - new insights and progress The current status and future directions of hepatitis B antiviral drug discovery.Use of Current and New Endpoints in the Evaluation of Experimental Hepatitis B Therapeutics.Hepatitis A to E: what's new?New antivirals for the treatment of chronic hepatitis B.HIV-hepatitis B virus co-infection: epidemiology, pathogenesis, and treatment.Immune checkpoint inhibitors: Navigating a new paradigm of treatment toxicities.A research agenda for curing chronic hepatitis B virus infection.Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and Liver.Epigenetic Regulation of Hepatitis B Virus Covalently Closed Circular DNA: Implications for Epigenetic Therapy against Chronic Hepatitis B.Prevalence of chronic kidney disease in patients with chronic hepatitis B: A cross-sectional survey.Discovery and Mechanistic Study of Benzamide Derivatives That Modulate Hepatitis B Virus Capsid Assembly.Five-year efficacy and safety of tenofovir-based salvage therapy for patients with chronic hepatitis B who previously failed LAM/ADV therapy.Induction of IFN-λ3 as an additional effect of nucleotide, not nucleoside, analogues: a new potential target for HBV infection.Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions.Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA.[Vaccination against hepatitis B: success and challenges].New horizon for radical cure of chronic hepatitis B virus infection.Hepatitis B virus: is a cure possible?A Series of Oleanolic Acid Derivatives as Anti-Hepatitis B Virus Agents: Design, Synthesis, and in Vitro and in Vivo Biological Evaluation.Characterization of novel hepadnaviral RNA species accumulated in hepatoma cells treated with viral DNA polymerase inhibitors A potent human neutralizing antibody Fc-dependently reduces established HBV infections

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Present and future therapies of hepatitis B: From discovery to cure

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Brian J McMahon

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Ju-Tao Guo

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Kyong-Mi Chang

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Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

APOBEC3 proteins mediate the clearance of foreign DNA from human cells

Inhibition of human hepatitis B virus replication by AT-61, a phenylpropenamide derivative, alone and in combination with (-)beta-L-2',3'-dideoxy-3'-thiacytidine

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

Hepatitis B prevention, diagnosis, treatment and care: a review

Interferon-inducible antiviral effectors

Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

Assembly-Directed Antivirals Differentially Bind Quasiequivalent Pockets to Modify Hepatitis B Virus Capsid Tertiary and Quaternary Structure

Intrahepatic hepatitis B virus covalently closed circular DNA can be a predictor of sustained response to therapy

The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes

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