Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts - Wikidata - wikimedia - TriplyDB

Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts

Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts

http://www.wikidata.org/entity/Q36379584

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Performance of urine cotinine and hypomethylation of AHRR and F2RL3 as biomarkers for smoking exposure in a population-based cohort.Establishment of a Strong Link Between Smoking and Cancer Pathogenesis through DNA Methylation Analysis.Integrated Analysis of Genome-Wide Copy Number Alterations and Gene Expression Profiling of Lung Cancer in Xuanwei, China Transgenic Overexpression of Aryl Hydrocarbon Receptor Repressor (AhRR) and AhR-Mediated Induction of CYP1A1, Cytokines, and Acute Toxicity Smoking-associated DNA methylation markers predict lung cancer incidence.Oral Cell DNA Adducts as Potential Biomarkers for Lung Cancer Susceptibility in Cigarette Smokers.Epigenome-wide association study of smoking and DNA methylation in non-small cell lung neoplasms.Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers.Hypermethylation of adjacent CpG sites is negatively correlated with the expression of lineage oncogene ASCL1 in pulmonary neuroendocrine tumors.AHRR (cg05575921) hypomethylation marks smoking behaviour, morbidity and mortality.DNA methylome analysis reveals distinct epigenetic patterns of ascending aortic dissection and bicuspid aortic valve.Gene expression profiling of epigenetic chromatin modification enzymes and histone marks by cigarette smoke: implications for COPD and lung cancer.Challenges and novel approaches for investigating molecular mediation.High Spicy Food Intake and Risk of Cancer: A Meta-analysis of Case-control Studies.Roadmap for investigating epigenome deregulation and environmental origins of cancer.Is cellular heterogeneity merely a confounder to be removed from epigenome-wide association studies?Cohort Profile: The Melbourne Collaborative Cohort Study (Health 2020).Accuracy and utility of an epigenetic biomarker for smoking in populations with varying rates of false self-report.DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk.Comparison and combination of blood DNA methylation at smoking-associated genes and at lung cancer-related genes in prediction of lung cancer mortality.Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study.Epigenome-wide association studies for breast cancer risk and risk factors.The most important questions in cancer research and clinical oncology-Question 2-5. Obesity-related cancers: more questions than answers Systems-epigenomics inference of transcription factor activity implicates aryl-hydrocarbon-receptor inactivation as a key event in lung cancer development.DNA methylation signatures of illicit drug injection and hepatitis C are associated with HIV frailty.Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies.Oxidative stress and inflammation mediate the effect of air pollution on cardio- and cerebrovascular disease: A prospective study in nonsmokers.Statistical and integrative system-level analysis of DNA methylation data.Testing for the indirect effect under the null for genome-wide mediation analyses.Causal effect of smoking on DNA methylation in peripheral blood: a twin and family study.[Progress of Epigenetic Methylation in Lung Cancer Research].Epigenetics as a mechanism linking developmental exposures to long-term toxicity.Methylomic survival predictors, frailty, and mortality.ASB1 differential methylation in ischaemic cardiomyopathy: relationship with left ventricular performance in end-stage heart failure patients.Identification of Smoking-Associated Differentially Methylated Regions Using Reduced Representation Bisulfite Sequencing and Cell type-Specific Enhancer Activation and Gene Expression.DNA Methylation Patterns in Normal Tissue Correlate more Strongly with Breast Cancer Status than Copy-Number Variants.DNA methylation of the cancer-related genes F2RL3 and AHRR is associated with occupational exposure to polycyclic aromatic hydrocarbons.Activation of PAR4 Upregulates p16 through Inhibition of DNMT1 and HDAC2 Expression via MAPK Signals in Esophageal Squamous Cell Carcinoma Cells Association of internal smoking dose with blood DNA methylation in three racial/ethnic populations Tobacco biomarkers and genetic/epigenetic analysis to investigate ethnic/racial differences in lung cancer risk among smokers

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Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts

http://www.wikidata.org/entity/Q36379584

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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Hypomethylation of smoking-rel ...... er in four prospective cohorts

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Hypomethylation of smoking-rel ...... er in four prospective cohorts

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Nature Communications

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Hypomethylation of smoking-rel ...... er in four prospective cohorts

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Christian Faltus

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Erica Ponzi

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Florence Guida

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Francesca Fasanelli

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Manuela Bianca Assumma

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Marc Chadeau-Hyam

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Mikael Johansson

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Philip C Haycock

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Silvia Polidoro

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Torkjel M Sandanger

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Projections of global mortality and burden of disease from 2002 to 2030

Tobacco and cancer: recent epidemiological evidence

SWAN: Subset-quantile within array normalization for illumina infinium HumanMethylation450 BeadChips

Genomic impact of cigarette smoke, with application to three smoking-related diseases

Identifiability and exchangeability for direct and indirect effects

Effect modification of the association of cumulative exposure and cancer risk by intensity of exposure and time since exposure cessation: a flexible method applied to cigarette smoking and lung cancer in the SYNERGY Study

The aryl hydrocarbon receptor complex

DNA methylation arrays as surrogate measures of cell mixture distribution.

Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking.

Functional normalization of 450k methylation array data improves replication in large cancer studies.

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10192

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10.1038/NCOMMS10192

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6

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Gianluca Severi

Graham G. Giles

Allison M Hodge

Caroline L. Relton

Kjell Grankvist

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2015-12-15T00:00:00Z

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287202907

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26667048

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4682166

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