Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease.
about
Electron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial BioenergeticsPGC-1α, mitochondrial dysfunction, and Huntington's diseaseDevelopment of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases.Activation of Autophagic Flux against Xenoestrogen Bisphenol-A-induced Hippocampal Neurodegeneration via AMP kinase (AMPK)/Mammalian Target of Rapamycin (mTOR) Pathways.Ethosuximide Induces Hippocampal Neurogenesis and Reverses Cognitive Deficits in an Amyloid-β Toxin-induced Alzheimer Rat Model via the Phosphatidylinositol 3-Kinase (PI3K)/Akt/Wnt/β-Catenin PathwayEarly-onset sleep defects in Drosophila models of Huntington's disease reflect alterations of PKA/CREB signaling.Methyl-Arginine Profile of Brain from Aged PINK1-KO+A53T-SNCA Mice Suggests Altered Mitochondrial Biogenesis.Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington's disease models.Quercetin improves the activity of the ubiquitin-proteasomal system in 150Q mutated huntingtin-expressing cells but exerts detrimental effects on neuronal survivability.Deregulation of CRTCs in Aging and Age-Related Disease Risk.In silico analysis of regulatory networks underlines the role of miR-10b-5p and its target BDNF in huntington's disease.Dynamin-related Protein 1 Inhibition Mitigates Bisphenol A-mediated Alterations in Mitochondrial Dynamics and Neural Stem Cell Proliferation and Differentiation.Inhibitory Effects of Bisphenol-A on Neural Stem Cells Proliferation and Differentiation in the Rat Brain Are Dependent on Wnt/β-Catenin Pathway.PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model.Neuroprotective Role of Novel Triazine Derivatives by Activating Wnt/β Catenin Signaling Pathway in Rodent Models of Alzheimer's Disease.Nigral dopaminergic PAK4 prevents neurodegeneration in rat models of Parkinson's disease.Transcriptional Dysregulation and Post-translational Modifications in Polyglutamine Diseases: From Pathogenesis to Potential Therapeutic Strategies.Mitochondrial Quality Control in Neurodegenerative Diseases: Focus on Parkinson's Disease and Huntington's Disease.A Mitochondria-Associated Oxidative Stress Perspective on Huntington's Disease
P2860
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P2860
Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Transducer of regulated CREB-b ...... aired in Huntington's disease.
@ast
Transducer of regulated CREB-b ...... aired in Huntington's disease.
@en
type
label
Transducer of regulated CREB-b ...... aired in Huntington's disease.
@ast
Transducer of regulated CREB-b ...... aired in Huntington's disease.
@en
prefLabel
Transducer of regulated CREB-b ...... aired in Huntington's disease.
@ast
Transducer of regulated CREB-b ...... aired in Huntington's disease.
@en
P2093
P2860
P356
P1476
Transducer of regulated CREB-b ...... aired in Huntington's disease.
@en
P2093
Ashu Johri
Divya Mishra
M Flint Beal
Swati Agarwal
Thomas Hennessey
Yoon Seong Kim
P2860
P304
P356
10.1093/HMG/DDS178
P577
2012-05-15T00:00:00Z