Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4 - Wikidata - wikimedia - TriplyDB

Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4

Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4

http://www.wikidata.org/entity/Q36380382

about

Th2 cytokines and asthma. Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists.Antiviral T-cell therapy Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells B cells responses and cytokine production are regulated by their immune microenvironment A cellular calculus for signal integration by T cells Interleukin-15 prevents mouse mast cell apoptosis through STAT6-mediated Bcl-xL expression Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis Clonal expansion of freshly isolated CD4T cells by randomized peptides and identification of peptide ligands using combinatorial peptide libraries.CD4+ T cell subset differentiation and avidity setpoint are dictated by the interplay of cytokine and antigen mediated signals IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART.The dynamics of T-cell receptor repertoire diversity following thymus transplantation for DiGeorge anomaly Endogenously produced IL-4 nonredundantly stimulates CD8+ T cell proliferation.Potent intestinal Th17 priming through peripheral lipopolysaccharide-based immunization.Stat proteins control lymphocyte proliferation by regulating p27Kip1 expression.Contracting the 'mus cells'--does down-sizing suit us for diving into the memory pool?Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses.Homeostasis of alpha beta TCR+ T cells.The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation Burnet oration. T-cell survival and the role of cytokines.Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis.Modalities of interleukin-7-induced human immunodeficiency virus permissiveness in quiescent T lymphocytes Control of Bcl-2 expression by reactive oxygen species Expression of IL-15RA or an IL-15/IL-15RA fusion on CD8+ T cells modifies adoptively transferred T-cell function in cis Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes for adoptive immunotherapy of HPV-associated malignancies.Qualitative differences between naïve and memory T cells.Cytotoxic T lymphocytes as immune-therapy in haematological practice.Suppression of Foxo1 activity and down-modulation of CD62L (L-selectin) in HIV-1 infected resting CD4 T cells.Involvement of growth factors in thymic involution.B-cell homeostasis: digital survival or analog growth?The interleukin (IL)-2 family cytokines: survival and proliferation signaling pathways in T lymphocytes.Dysregulation of IL-15-mediated T-cell homeostasis in TGF-beta dominant-negative receptor transgenic mice.Skin-derived interleukin-7 contributes to the proliferation of lymphocytes in cutaneous T-cell lymphoma.Cytokine-induced survival of activated T cells in vitro and in vivo p47phox-deficient immune microenvironment signals dysregulate naive T-cell apoptosis.Screening for peptides targeted to IL-7Rα for molecular imaging of rheumatoid arthritis synovium Homeostasis and the age-associated defect of CD4 T cells.IL-7 as a potential therapy for HIV-1-infected individuals.Role of interleukin-7 in bone and T-cell homeostasis.A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules.Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling

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Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4

http://www.wikidata.org/entity/Q36380382

description

1997 nî lūn-bûn

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A Vella

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J Kappler

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T K Teague

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P2860

Requirements for interleukin-4-induced gene expression and functional characterization of Stat6

Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

Interleukin-4-induced STAT6 recognizes and activates a target site in the promoter of the interleukin-4 receptor gene

Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

An interleukin-4-induced transcription factor: IL-4 Stat

Essential role of Stat6 in IL-4 signalling

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

Bcl-XL and Bcl-2 repress a common pathway of cell death

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

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325-330

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10.1084/JEM.186.2.325

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2

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186

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Philippa Marrack

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13997362

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9221762

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2198981

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