Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function
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CD44 cell adhesion moleculesCell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesisCancer Stem Cell Hierarchy in Glioblastoma MultiformeCancer-stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasisInteractions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and CancerLoss of transgelin in breast and colon tumors and in RIE-1 cells by Ras deregulation of gene expression through Raf-independent pathwaysMetastasis: a question of life or deathMechanism and biological significance of CD44 cleavageHyaluronan production increases the malignant properties of mesothelioma cellsNon-small cell lung cancer cyclooxygenase-2-dependent invasion is mediated by CD44Molecular characterization of a novel intracellular hyaluronan-binding proteinExpression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathwayLoss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancerThe extracellular matrix: a dynamic niche in cancer progressionInhibition of Functional Hyaluronan-CD44 Interactions in CD133-positive Primary Human Ovarian Carcinoma Cells by Small Hyaluronan Oligosaccharides.Functional hierarchy of simultaneously expressed adhesion receptors: integrin alpha2beta1 but not CD44 mediates MV3 melanoma cell migration and matrix reorganization within three-dimensional hyaluronan-containing collagen matricesDevelopment of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking.Serum CD44 in non-Hodgkin's lymphoma.CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastomaModeling metastasis in the mouse.Dual roles of sialyl Lewis X oligosaccharides in tumor metastasis and rejection by natural killer cells.Angiopoietin-3 is tethered on the cell surface via heparan sulfate proteoglycansStromal hyaluronan interaction with epithelial CD44 variants promotes prostate cancer invasiveness by augmenting expression and function of hepatocyte growth factor and androgen receptorHyaluronan synthase elevation in metastatic prostate carcinoma cells correlates with hyaluronan surface retention, a prerequisite for rapid adhesion to bone marrow endothelial cells.Coupling of osteopontin and its cell surface receptor CD44 to the cell survival response elicited by interleukin-3 or granulocyte-macrophage colony-stimulating factor.CD44 upregulation in E-cadherin-negative esophageal cancers results in cell invasionSoluble CD44 interacts with intermediate filament protein vimentin on endothelial cell surface.Hyaluronan binding motifs of USP17 and SDS3 exhibit anti-tumor activity.Hypoxia as a biomarker for radioresistant cancer stem cells.sCD44 internalization in human trabecular meshwork cells.In vivo evidence for the role of CD44s in promoting breast cancer metastasis to the liver.Identification and characterization of CD44RC, a novel alternatively spliced soluble CD44 isoform that can potentiate the hyaluronan binding activity of cell surface CD44.CD44 as a receptor for colonization of the pharynx by group A Streptococcus.Downregulation of CD44 reduces doxorubicin resistance of CD44CD24 breast cancer cellsThe liberation of CD44.Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion.CD44 and HCELL: preventing hematogenous metastasis at step 1.Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progressionGrowth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expressionPerturbation of hyaluronan interactions by soluble CD44 inhibits growth of murine mammary carcinoma cells in ascites.
P2860
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P2860
Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Induction of apoptosis of meta ...... mor cell surface CD44 function
@ast
Induction of apoptosis of meta ...... mor cell surface CD44 function
@en
type
label
Induction of apoptosis of meta ...... mor cell surface CD44 function
@ast
Induction of apoptosis of meta ...... mor cell surface CD44 function
@en
prefLabel
Induction of apoptosis of meta ...... mor cell surface CD44 function
@ast
Induction of apoptosis of meta ...... mor cell surface CD44 function
@en
P2093
P2860
P356
P1476
Induction of apoptosis of meta ...... mor cell surface CD44 function
@en
P2093
P2860
P304
P356
10.1084/JEM.186.12.1985
P407
P577
1997-12-01T00:00:00Z