Interleukin 4 suppresses interleukin 2 and interferon gamma production by naive T cells stimulated by accessory cell-dependent receptor engagement
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Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulationMercuric chloride, a chemical responsible for T helper cell (Th)2-mediated autoimmunity in brown Norway rats, directly triggers T cells to produce interleukin-4Reciprocal modulation between microglia and astrocyte in reactive gliosis following the CNS injuryType I (insulin-dependent) diabetes is a Th1- and Th2-mediated autoimmune diseaseAn alternate mechanism of glucocorticoid anti-proliferative effect: promotion of a Th2 cytokine-secreting profile.IgE receptor-positive non-B/non-T cells dominate the production of interleukin 4 and interleukin 6 in immunized mice.Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals.Transcriptional and post-transcriptional mechanisms of glucocorticoid antiproliferative effects.Dual role of interleukin-4 (IL-4) in pulmonary paracoccidioidomycosis: endogenous IL-4 can induce protection or exacerbation of disease depending on the host genetic pattern.Suppressed T helper 2 immunity and prolonged survival of a nematode parasite in protein-malnourished mice.Regulation of IL4 gene expression by T cells and therapeutic perspectives.A Toxoplasma gondii-derived factor(s) stimulates immune downregulation: an in vitro modelInterleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor alpha subunit.Enhanced resistance in STAT6-deficient mice to infection with ectromelia virusLeishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection.Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity.CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania majorCD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles.Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion.A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cellsMolecular regulation of human interleukin 2 and T-cell function by interleukin 4IL-4: an important cytokine in determining the fate of T cells.IgE-mediated antigen presentation.Localization of soluble major histocompatibility class II-peptide complexes on T cell surface.Gene gun bombardment with DNA-coated golden particles enhanced the protective effect of a DNA vaccine based on thioredoxin glutathione reductase of Schistosoma japonicum.Protective effect of rPb40 as an adjuvant for chemotherapy in experimental paracoccidioidomycosis.Protective effect of exogenous recombinant mouse interferon-gamma and tumour necrosis factor-alpha on ectromelia virus infection in susceptible BALB/c mice.Cyclosporin A increases IFN-gamma production by T cells when co-stimulated through CD28.Gene--gene interaction among cytokine polymorphisms influence susceptibility to aggressive periodontitis.Interleukin-12-responding asialoGM1+CD8+ central memory-type T cells as precursor cells for interferon-gamma-producing killer T cells.Increased activation and altered ratio of interferon-gamma: interleukin-4 secreting cells in MRL-lpr/lpr mice.Differences in cytokine synthesis by the sub-populations of dendritic cells from afferent lymph.Protective mechanisms against the intestinal nematode Strongyloides venezuelensis in Schistosoma japonicum-infected mice.Endogenous interleukin-4 does not suppress the resistance against a primary or a secondary Listeria monocytogenes infection in mice.
P2860
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P2860
Interleukin 4 suppresses interleukin 2 and interferon gamma production by naive T cells stimulated by accessory cell-dependent receptor engagement
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Interleukin 4 suppresses inter ...... -dependent receptor engagement
@ast
Interleukin 4 suppresses inter ...... -dependent receptor engagement
@en
type
label
Interleukin 4 suppresses inter ...... -dependent receptor engagement
@ast
Interleukin 4 suppresses inter ...... -dependent receptor engagement
@en
prefLabel
Interleukin 4 suppresses inter ...... -dependent receptor engagement
@ast
Interleukin 4 suppresses inter ...... -dependent receptor engagement
@en
P2093
P2860
P356
P1476
Interleukin 4 suppresses inter ...... -dependent receptor engagement
@en
P2093
Fazekas de St Groth B
P2860
P304
P356
10.1073/PNAS.90.13.5914
P407
P577
1993-07-01T00:00:00Z