Tim-3-expressing CD4+ and CD8+ T cells in human tuberculosis (TB) exhibit polarized effector memory phenotypes and stronger anti-TB effector functions.
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Modulation of Innate Immune Mechanisms to Enhance Leishmania Vaccine-Induced Immunity: Role of Coinhibitory MoleculesRole of Tim-3 in hepatitis B virus infection: An overviewTim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infectionElevated OPN, IP-10, and neutrophilia in loop-mediated isothermal amplification confirmed tuberculosis patients.CD4+ T cells contain early extrapulmonary tuberculosis (TB) dissemination and rapid TB progression and sustain multieffector functions of CD8+ T and CD3- lymphocytes: mechanisms of CD4+ T cell immunity.Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers.Tim-3 and its role in regulating anti-tumor immunity.Regulation of T cell responses by the receptor molecule Tim-3.A combination trial of vaccine plus ipilimumab in metastatic castration-resistant prostate cancer patients: immune correlates.Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus.Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection.Patients with tuberculosis disease have Mycobacterium tuberculosis-specific CD8 T cells with a pro-apoptotic phenotype and impaired proliferative capacity, which is not restored following treatment.Up-regulation of Tim-3 on T cells during acute simian immunodeficiency virus infection and on antigen specific responders.Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression.T cell exhaustion during persistent viral infections.Accumulation of Cytotoxic CD16+ NK Cells in Simian Immunodeficiency Virus-Infected Lymph Nodes Associated with In Situ Differentiation and Functional Anergy.Inhibitory Receptors Beyond T Cell Exhaustion.Long noncoding RNA derived from CD244 signaling epigenetically controls CD8+ T-cell immune responses in tuberculosis infection.TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection.Tuberculous pleurisy drives marked effector responses of γδ, CD4+, and CD8+ T cell subpopulations in humans.Apoptosis of tumor infiltrating effector TIM-3+CD8+ T cells in colon cancerPD-1 and Tim-3 pathways are associated with regulatory CD8+ T-cell function in decidua and maintenance of normal pregnancyInhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than "Exhaustion" of Human CD8 T Cells.Immunological Roles of Elevated Plasma Levels of Matricellular Proteins in Japanese Patients with Pulmonary Tuberculosis.Modulation of Tim-3 Expression by Antigen-Dependent and -Independent Factors on T Cells from Patients with Chronic Hepatitis B Virus Infection.In search of a new paradigm for protective immunity to TBToo much of a good thing? Tim-3 and TCR signaling in T cell exhaustion.Enhanced Expression of T-Cell Immunoglobulin and Mucin Domain Protein 3 in Endothelial Cells Facilitates Intracellular Killing of Rickettsia heilongjiangensis.Differential Expression of Immune Checkpoint Modulators on In Vitro Primed CD4(+) and CD8(+) T Cells.Mycobacterium tuberculosis Prolyl Oligopeptidase Induces In vitro Secretion of Proinflammatory Cytokines by Peritoneal Macrophages.T-cell exhaustion in tuberculosis: pitfalls and prospects.Selective Destruction of Interleukin 23-Induced Expansion of a Major Antigen-Specific γδ T-Cell Subset in Patients With Tuberculosis.Programmed cell death-1 (PD-1) and T-cell immunoglobulin mucin-3 (Tim-3) regulate CD4+ T cells to induce Type 2 helper T cell (Th2) bias at the maternal-fetal interface.TIM-3 Engagement Promotes Effector Memory T Cell Differentiation of Human Antigen-Specific CD8 T Cells by Activating mTORC1.Acute Stimulation Generates Tim-3-expressing Th1-type CD4 T Cells That Persist In Vivo and Show Enhanced Effector Function.Tim-3 co-stimulation promotes short-lived effector T cells, restricts memory precursors, and is dispensable for T cell exhaustion.Characterization of the cryoablation-induced immune response in kidney cancer patients.Immune regulation by Tim-3.Immune checkpoint receptors: homeostatic regulators of immunity.Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.
P2860
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P2860
Tim-3-expressing CD4+ and CD8+ T cells in human tuberculosis (TB) exhibit polarized effector memory phenotypes and stronger anti-TB effector functions.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Tim-3-expressing CD4+ and CD8+ ...... er anti-TB effector functions.
@ast
Tim-3-expressing CD4+ and CD8+ ...... er anti-TB effector functions.
@en
type
label
Tim-3-expressing CD4+ and CD8+ ...... er anti-TB effector functions.
@ast
Tim-3-expressing CD4+ and CD8+ ...... er anti-TB effector functions.
@en
prefLabel
Tim-3-expressing CD4+ and CD8+ ...... er anti-TB effector functions.
@ast
Tim-3-expressing CD4+ and CD8+ ...... er anti-TB effector functions.
@en
P2093
P2860
P1433
P1476
Tim-3-expressing CD4+ and CD8+ ...... er anti-TB effector functions.
@en
P2093
Boping Zhou
Crystal Y Chen
Danyun Fang
Gucheng Zeng
Hongying Liao
Jianbo Chen
P2860
P304
P356
10.1371/JOURNAL.PPAT.1002984
P577
2012-11-08T00:00:00Z