DNA adduct-induced stabilization of slipped frameshift intermediates within repetitive sequences: implications for mutagenesis.
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All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesisDNA Sequence Modulates the Conformation of the Food Mutagen 2-Amino-3-methylimidazo[4,5- f ]quinoline in the Recognition Sequence of the Nar I Restriction Enzyme † , ‡Mechanism of DNA polymerase II-mediated frameshift mutagenesisSpecific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridineEarly detection of 2-amino-1-methyl-6-phenylimidazo (4,5-b)pyridine(PhIP)-induced mutations within the Apc gene of rat colon.Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions.Development of a novel site-specific mutagenesis assay using MALDI-ToF MS (SSMA-MS).Energetic signatures of single base bulges: thermodynamic consequences and biological implications.Complex frameshift mutations mediated by plasmid pKM101: mutational mechanisms deduced from 4-aminobiphenyl-induced mutation spectra in Salmonella.Heterocyclic aromatic amine metabolism, DNA adduct formation, mutagenesis, and carcinogenesis.SOS factors involved in translesion synthesis.Inactivation of DNA proofreading obviates the need for SOS induction in frameshift mutagenesis.Cellular strategies for accommodating replication-hindering adducts in DNA: control by the SOS response in Escherichia coli.C8-linked bulky guanosine DNA adducts: experimental and computational insights into adduct conformational preferences and resulting mutagenicity.Adaptive Gene Loss? Tracing Back the Pseudogenization of the Rabbit CCL8 Chemokine.NMR evidence of the stabilisation by the carcinogen N-2-acetylaminofluorene of a frameshift mutagenesis intermediate.Recognition of DNA adducts by human nucleotide excision repair. Evidence for a thermodynamic probing mechanism.Comparative mutagenesis of the C8-guanine adducts of 1-nitropyrene and 1,6- and 1,8-dinitropyrene in a CpG repeat sequence. A slipped frameshift intermediate model for dinucleotide deletion.Mutational and DNA binding specificity of the carcinogen 2-amino-3, 8-dimethylimidazo[4,5-f]quinoxaline.
P2860
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P2860
DNA adduct-induced stabilization of slipped frameshift intermediates within repetitive sequences: implications for mutagenesis.
description
1993 nî lūn-bûn
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1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
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1993年學術文章
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1993年學術文章
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name
DNA adduct-induced stabilizati ...... implications for mutagenesis.
@ast
DNA adduct-induced stabilizati ...... implications for mutagenesis.
@en
type
label
DNA adduct-induced stabilizati ...... implications for mutagenesis.
@ast
DNA adduct-induced stabilizati ...... implications for mutagenesis.
@en
prefLabel
DNA adduct-induced stabilizati ...... implications for mutagenesis.
@ast
DNA adduct-induced stabilizati ...... implications for mutagenesis.
@en
P2093
P2860
P356
P1476
DNA adduct-induced stabilizati ...... implications for mutagenesis.
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.13.5989
P407
P577
1993-07-01T00:00:00Z