Tumor-derived autophagosome vaccine: mechanism of cross-presentation and therapeutic efficacy. - Wikidata - wikimedia - TriplyDB

Tumor-derived autophagosome vaccine: mechanism of cross-presentation and therapeutic efficacy.

Tumor-derived autophagosome vaccine: mechanism of cross-presentation and therapeutic efficacy.

http://www.wikidata.org/entity/Q36391595

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Glimpse into the future: harnessing autophagy to promote anti-tumor immunity with the DRibbles vaccine Autophagy-associated immune responses and cancer immunotherapy The Role of HMGB1 Signaling Pathway in the Development and Progression of Hepatocellular Carcinoma: A Review Pathways and therapeutic targets in melanoma Autophagy, autophagy-associated adaptive immune responses and its role in hematologic malignancies Nanomaterials and autophagy: new insights in cancer treatment Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory T cells Pathways of antigen processing.Trial Watch: Toll-like receptor agonists in oncological indications.Trial watch: Immunostimulatory cytokines in cancer therapy.Therapeutic antitumor efficacy of B cells loaded with tumor-derived autophagasomes vaccine (DRibbles)Tumor-derived autophagosomes (DRibbles) induce B cell activation in a TLR2-MyD88 dependent manner.HMGB1 in health and disease.Dendritic cell-based vaccines: barriers and opportunities An autophagosome-based therapeutic vaccine for HBV infection: a preclinical evaluation.Immunological significance of the accumulation of autophagy components in oral squamous cell carcinoma.Therapeutic antitumor efficacy of tumor-derived autophagosome (DRibble) vaccine on head and neck cancer.Variable epitope library carrying heavily mutated survivin-derived CTL epitope variants as a new class of efficient vaccine immunogen tested in a mouse model of breast cancer.Ubiquitinated proteins enriched from tumor cells by a ubiquitin binding protein Vx3(A7) as a potent cancer vaccine.Of LAP, CUPS, and DRibbles - Unconventional Use of Autophagy Proteins for MHC Restricted Antigen Presentation Antigen Cross-Priming of Cell-Associated Proteins is Enhanced by Macroautophagy within the Antigen Donor Cell.Sampling From the Proteome to the Human Leukocyte Antigen-DR (HLA-DR) Ligandome Proceeds Via High Specificity Tumor-released autophagosomes induce IL-10-producing B cells with suppressive activity on T lymphocytes via TLR2-MyD88-NF-κB signal pathway.Peptidases released by necrotic cells control CD8+ T cell cross-priming.Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5.Combinational Immunotherapy with Allo-DRibble Vaccines and Anti-OX40 Co-Stimulation Leads to Generation of Cross-Reactive Effector T Cells and Tumor Regression.The Autophagic Machinery in Viral Exocytosis.Oncolytic Immunotherapy: Dying the Right Way is a Key to Eliciting Potent Antitumor Immunity.Targeting the acute myeloid leukemic stem cell compartment by enhancing tumor cell-based vaccines.The impact of macroautophagy on CD8(+) T-cell-mediated antiviral immunity.Immunogenicity of necrotic cell death.Autophagy as a Stress Response Pathway in the Immune System.Autophagy proteins in antigen processing for presentation on MHC molecules.Dying cells actively regulate adaptive immune responses.TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles).Sorafenib and a novel immune therapy in lung metastasis from hepatocellular carcinoma following hepatectomy: A case report.Tumor SQSTM1 (p62) expression and T cells in colorectal cancer.Immune responses of dendritic cells combined with tumor-derived autophagosome vaccine on hepatocellular carcinoma.Autophagy-assisted antigen cross-presentation: Autophagosome as the argo of shared tumor-specific antigens and DAMPs.

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Tumor-derived autophagosome vaccine: mechanism of cross-presentation and therapeutic efficacy.

http://www.wikidata.org/entity/Q36391595

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Clinical Cancer Research

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Tumor-derived autophagosome va ...... tion and therapeutic efficacy.

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Bernard A Fox

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Daniel Haley

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Hong-Ming Hu

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Li-Xin Wang

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Puiyi Pang

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Sandra Aung

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Walter J Urba

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Yuhuan Li

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Zhihua Cui

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P2860

CLEC9A is a novel activation C-type lectin-like receptor expressed on BDCA3+ dendritic cells and a subset of monocytes

Autophagy: molecular machinery for self-eating

ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells

Phagosomes are competent organelles for antigen cross-presentation

The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation

Role of autophagy in cancer

Pathways of clathrin-independent endocytosis

Efficient cross-presentation depends on autophagy in tumor cells.

Cross-presentation, dendritic cells, tolerance and immunity.

Defective ribosomal products (DRiPs): a major source of antigenic peptides for MHC class I molecules?

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