Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins
about
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damageCrystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modificationOxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTOCrystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNAProtein arginine methyltransferase 7 regulates cellular response to DNA damage by methylating promoter histones H2A and H4 of the polymerase δ catalytic subunit gene, POLD1A possible link between iron deficiency and gastrointestinal carcinogenesis.Alternative Pathway for the Reaction Catalyzed by DNA Dealkylase AlkB from Ab Initio QM/MM CalculationsHomology modeling, molecular dynamics, and site-directed mutagenesis study of AlkB human homolog 1 (ALKBH1)Structure and Mechanism of a Viral Collagen Prolyl HydroxylaseTET family proteins: oxidation activity, interacting molecules, and functions in diseases.Alkbh2 protects against lethality and mutation in primary mouse embryonic fibroblasts.S-alkylthiolation of O6-methylguanine-DNA-methyltransferase (MGMT) to sensitize cancer cells to anticancer therapy.Transcription increases methylmethane sulfonate-induced mutations in alkB strains of Escherichia coli.Damage detection and base flipping in direct DNA alkylation repair.Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι.Quantum mechanics/molecular mechanics study on the oxygen binding and substrate hydroxylation step in AlkB repair enzymesNucleic acid oxidation in DNA damage repair and epigeneticsDown-regulation of ALKBH2 increases cisplatin sensitivity in H1299 lung cancer cells.Oxidative demethylation of DNA and RNA mediated by non-heme iron-dependent dioxygenases.ALKBH2, a novel AlkB homologue, contributes to human bladder cancer progression by regulating MUC1 expression.Frequent down-regulation of hABH2 in gastric cancer and its involvement in growth of cancer cells.O2 -independent demethylation of trimethylamine N-oxide by Tdm of Methylocella silvestris.
P2860
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P2860
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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2006年學術文章
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name
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins
@ast
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins
@en
type
label
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins
@ast
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins
@en
prefLabel
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins
@ast
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins
@en
P2860
P1476
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins
@en
P2093
Yukiko Mishina
P2860
P304
P356
10.1016/J.JINORGBIO.2005.12.018
P577
2006-02-15T00:00:00Z