about
Dynamic changes of driver genes' mutations across clinical stages in nine cancer typesExpression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R.Mouse models of PIK3CA mutations: one mutation initiates heterogeneous mammary tumors.Inhibitors of STAT3, β-catenin, and IGF-1R sensitize mouse PIK3CA-mutant breast cancer to PI3K inhibitors.Genes with mutation significance were highly associated with the clinical pattern of patients with breast cancer.A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens.
P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Initiating breast cancer by PIK3CA mutation
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Initiating breast cancer by PIK3CA mutation
@en
type
label
Initiating breast cancer by PIK3CA mutation
@ast
Initiating breast cancer by PIK3CA mutation
@en
prefLabel
Initiating breast cancer by PIK3CA mutation
@ast
Initiating breast cancer by PIK3CA mutation
@en
P2860
P356
P1476
Initiating breast cancer by PIK3CA mutation
@en
P2093
Todd W Miller
P2860
P2888
P356
10.1186/BCR3103
P577
2012-02-07T00:00:00Z
P5875
P6179
1018183934