Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation
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Deletion of STK40 protein in mice causes respiratory failure and death at birth.Deletion of Shp2 in bronchial epithelial cells impairs IL-25 production in vitro, but has minor influence on asthmatic inflammation in vivo.Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuriaSHP2 positively regulates TGFβ1-induced epithelial-mesenchymal transition modulated by its novel interacting protein Hook1.Phenotypic modulation of corpus cavernosum smooth muscle cells in a rat model of cavernous neurectomySH2 domain-containing protein tyrosine phosphatase 2 and focal adhesion kinase protein interactions regulate pulmonary endothelium barrier function.Conditional Knockout of Src Homology 2 Domain-containing Protein Tyrosine Phosphatase-2 in Myeloid Cells Attenuates Renal Fibrosis after Unilateral Ureter Obstruction.Eosinophil differentiation in the bone marrow is promoted by protein tyrosine phosphatase SHP2.The glutathione peroxidase 1-protein tyrosine phosphatase 1B-protein phosphatase 2A axis. A key determinant of airway inflammation and alveolar destruction.Chronic Cigarette Smoke Mediated Global Changes in Lung Mucoepidermoid Cells: A Phosphoproteomic Analysis.Cigarette smoke extract-induced BEAS-2B cell apoptosis and anti-oxidative Nrf-2 up-regulation are mediated by ROS-stimulated p38 activation.Src homology 2-containing protein tyrosine phosphatase-2 acts as a negative regulator for MUC5AC transcription via the inhibition of the ERK1/2 MAPK signalling pathway in the airway.Shp2 Deficiency Impairs the Inflammatory Response Against Haemophilus influenzae by Regulating Macrophage Polarization.Inhibition of endoplasmic reticulum stress alleviates cigarette smoke-induced airway inflammation and emphysema.Effect of Phospholipid Transfer Protein on Cigarette Smoke Extract-Induced IL-8 Production in Human Pulmonary Epithelial Cells.SHP2 inhibitor PHPS1 protects against atherosclerosis by inhibiting smooth muscle cell proliferation.Sodium Tanshinone IIA Sulfonate Decreases Cigarette Smoke-Induced Inflammation and Oxidative Stress via Blocking the Activation of MAPK/HIF-1α Signaling Pathway.
P2860
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P2860
Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation
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2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation
@ast
Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation
@en
type
label
Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation
@ast
Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation
@en
prefLabel
Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation
@ast
Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation
@en
P2093
P2860
P356
P1476
Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation
@en
P2093
Fen-Fen Li
Huahao Shen
Hui-Juan Shen
Jun-Xia Jiang
Lin-Hui Zhang
Meng-Jing Bao
Qiang-Min Xie
P2860
P304
P356
10.4049/JIMMUNOL.1200197
P407
P50
P577
2012-08-13T00:00:00Z