Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer.
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Colorectal Carcinogenesis, Radiation Quality, and the Ubiquitin-Proteasome PathwayLow-grade slightly elevated and polypoid colorectal adenomas display differential β-catenin-TCF/LEF activity, c-Myc, and cyclin D1 expression.Aspirin inhibits epithelial-to-mesenchymal transition and migration of oncogenic K-ras-expressing non-small cell lung carcinoma cells by down-regulating E-cadherin repressor Slug.Computational Identification of Key Regulators in Two Different Colorectal Cancer Cell Lines.Salinomycin inhibits metastatic colorectal cancer growth and interferes with Wnt/β-catenin signaling in CD133(+) human colorectal cancer cells.Conventional colon adenomas harbor various disturbances in microsatellite stability and contain micro-serrated foci with microsatellite instability.Oncogenic KRAS activates an embryonic stem cell-like program in human colon cancer initiationColorectal cancer risk genes are functionally enriched in regulatory pathways.Filtered selection coupled with support vector machines generate a functionally relevant prediction model for colorectal cancer.Human telomerase reverse transcriptase (hTERT) promotes gastric cancer invasion through cooperating with c-Myc to upregulate heparanase expressionCancer stem cell drugs target K-ras signaling in a stemness context.miR-217 regulates tumor growth and apoptosis by targeting the MAPK signaling pathway in colorectal cancer.miR-450b-5p induced by oncogenic KRAS is required for colorectal cancer progression.SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development.Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression.Chemical inhibition reveals differential requirements of signaling pathways in krasV12- and Myc-induced liver tumors in transgenic zebrafish.Induction of immunoglobulin transcription factor 2 and resistance to MEK inhibitor in melanoma cells.Harnessing low-density lipoprotein receptor protein 6 (LRP6) genetic variation and Wnt signaling for innovative diagnostics in complex diseases.Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.K-ras Mutations as the Earliest Driving Force in a Subset of Colorectal Carcinomas.The MAPK Pathway Regulates Intrinsic Resistance to BET Inhibitors in Colorectal Cancer.Ras signaling through RASSF proteins.A New View of Pathway-Driven Drug Resistance in Tumor Proliferation.Obstacles Posed by the Tumor Microenvironment to T cell Activity: A Case for Synergistic Therapies.Hypoxia Inducible Factor (HIF) Hydroxylases as Regulators of Intestinal Epithelial Barrier Function.Independent and core pathways in oncogenic KRAS signaling.TrkC promotes colorectal cancer growth and metastasis.LRP6 is identified as a potential prognostic marker for oral squamous cell carcinoma via MALDI-IMS.Repurposing Established Compounds to Target Pancreatic Cancer Stem Cells (CSCs).Hilbert-Schmidt and Sobol sensitivity indices for static and time series Wnt signaling measurements in colorectal cancer - part A.Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration.LRP6 promotes invasion and metastasis of colorectal cancer through cytoskeleton dynamics.MicroRNA-binding site polymorphisms in genes involved in colorectal cancer etiopathogenesis and their impact on disease prognosis.β-Catenin mRNA Silencing and MEK Inhibition Display Synergistic Efficacy in Preclinical Tumor Models.Pattern of LRP6 gene expression in tumoral tissues of colorectal cancer.Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple.BAG3 promotes chondrosarcoma progression by upregulating the expression of β-catenin.SMAR1 inhibits Wnt/β-catenin signaling and prevents colorectal cancer progression.Identification of RSPO2 Fusion Mutations and Target Therapy Using a Porcupine Inhibitor
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P2860
Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
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2014年學術文章
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name
Oncogenic KRAS signalling prom ...... ugh LRP6 in colorectal cancer.
@ast
Oncogenic KRAS signalling prom ...... ugh LRP6 in colorectal cancer.
@en
type
label
Oncogenic KRAS signalling prom ...... ugh LRP6 in colorectal cancer.
@ast
Oncogenic KRAS signalling prom ...... ugh LRP6 in colorectal cancer.
@en
prefLabel
Oncogenic KRAS signalling prom ...... ugh LRP6 in colorectal cancer.
@ast
Oncogenic KRAS signalling prom ...... ugh LRP6 in colorectal cancer.
@en
P2093
P2860
P356
P1433
P1476
Oncogenic KRAS signalling prom ...... ugh LRP6 in colorectal cancer.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2014.416
P407
P577
2014-12-15T00:00:00Z