ClpB N-terminal domain plays a regulatory role in protein disaggregation
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Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocationEfficient production of (2)H, (13)C, (15)N-enriched industrial enzyme Rhizopus chinensis lipase with native disulfide bonds.Substrate Discrimination by ClpB and Hsp104.Characterization of the molecular chaperone ClpB from the pathogenic spirochaete Leptospira interrogansDynamical Structures of Hsp70 and Hsp70-Hsp40 Complexes.Crystal structures of Hsp104 N-terminal domains from Saccharomyces cerevisiae and Candida albicans suggest the mechanism for the function of Hsp104 in dissolving prions.Overlapping and Specific Functions of the Hsp104 N Domain Define Its Role in Protein Disaggregation.Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.Fusion protein analysis reveals the precise regulation between Hsp70 and Hsp100 during protein disaggregation.Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control.Stand-alone ClpG disaggregase confers superior heat tolerance to bacteria.Probing the cooperativity of Thermoplasma acidophilum proteasome core particle gating by NMR spectroscopy.Isolation and Identification of Putative Protein Substrates of the AAA+ Molecular Chaperone ClpB from the Pathogenic Spirochaete Leptospira interrogans.The amino-terminal domain of ClpB protein plays a crucial role in its substrate disaggregation activity
P2860
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P2860
ClpB N-terminal domain plays a regulatory role in protein disaggregation
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2015 nî lūn-bûn
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2015年の論文
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name
ClpB N-terminal domain plays a regulatory role in protein disaggregation
@ast
ClpB N-terminal domain plays a regulatory role in protein disaggregation
@en
type
label
ClpB N-terminal domain plays a regulatory role in protein disaggregation
@ast
ClpB N-terminal domain plays a regulatory role in protein disaggregation
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prefLabel
ClpB N-terminal domain plays a regulatory role in protein disaggregation
@ast
ClpB N-terminal domain plays a regulatory role in protein disaggregation
@en
P2093
P2860
P356
P1476
ClpB N-terminal domain plays a regulatory role in protein disaggregation
@en
P2093
Algirdas Velyvis
Enrico Rennella
Patrick Farber
Rina Rosenzweig
P2860
P304
P356
10.1073/PNAS.1512783112
P407
P577
2015-11-30T00:00:00Z