T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.
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Prognosis of hormone-dependent breast cancers: implications of the presence of dysfunctional transcriptional networks activated by insulin via the immune transcription factor T-betCD70 and IFN-1 selectively induce eomesodermin or T-bet and synergize to promote CD8+ T-cell responses.Interleukin 27 inhibits cytotoxic T-lymphocyte-mediated platelet destruction in primary immune thrombocytopenia.The role of the Th1 transcription factor T-bet in a mouse model of immune-mediated bone-marrow failureIncreased memory conversion of naïve CD8 T cells activated during late phases of acute virus infection due to decreased cumulative antigen exposure.Inflammation programs self-reactive CD8+ T cells to acquire T-box-mediated effector function but does not prevent deletional toleranceTranscription factor T-bet regulates inflammatory arthritis through its function in dendritic cells.CXCR3 in T cell function.Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression.Transcriptional control of rapid recall by memory CD4 T cells.More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases.CD8(+)IL-17(+) T Cells Mediate Neutrophilic Airway Obliteration in T-bet-Deficient Mouse Lung Allograft Recipients.Identification of a distant T-bet enhancer responsive to IL-12/Stat4 and IFNgamma/Stat1 signals.Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor.Urinary bladder epithelium antigen induces CD8+ T cell tolerance, activation, and autoimmune response.Interferon regulatory factor 8 integrates T-cell receptor and cytokine-signaling pathways and drives effector differentiation of CD8 T cellsT-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.Autoimmunity: basic mechanisms and implications in endocrine diseases. Part I.Not-so-great expectations: re-assessing the essence of T-cell memory.Network model of survival signaling in large granular lymphocyte leukemia.Tbet or Continued RORγt Expression Is Not Required for Th17-Associated Immunopathology.A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathyAll-trans retinoic acid inhibits type 1 diabetes by T regulatory (Treg)-dependent suppression of interferon-gamma-producing T-cells without affecting Th17 cells.The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression.T-bet is essential for encephalitogenicity of both Th1 and Th17 cellsFunctional Th1 cells are required for surgical adhesion formation in a murine model.T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function.CXCR3 deficiency increases susceptibility to genital herpes simplex virus type 2 infection: Uncoupling of CD8+ T-cell effector function but not migration.Biochemical signaling pathways for memory T cell recall.A pivotal role for interleukin-27 in CD8+ T cell functions and generation of cytotoxic T lymphocytes.T-bet in disease.A common promoter variant of TBX21 is associated with allele specific binding to Yin-Yang 1 and reduced gene expression.T cell affinity regulates asymmetric division, effector cell differentiation, and tissue pathology.Diverse roles for T-bet in the effector responses required for resistance to infection.T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.A crucial role for T-bet in selectin ligand expression in T helper 1 (Th1) cells.T-bet is required for protection against vaccinia virus infection.T-bet protects against exacerbation of schistosome egg-induced immunopathology by regulating Th17-mediated inflammation.
P2860
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P2860
T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.
@ast
T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.
@en
type
label
T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.
@ast
T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.
@en
prefLabel
T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.
@ast
T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.
@en
P2093
P2860
P356
P1476
T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.
@en
P2093
Amy E Juedes
Evelyn Rodrigo
Laurie H Glimcher
Lisa Togher
Matthias G von Herrath
P2860
P304
P356
10.1084/JEM.20031873
P407
P577
2004-04-01T00:00:00Z