KN-93 inhibits IKr in mammalian cardiomyocytes.

Item

http://www.wikidata.org/entity/Q36399822

description

2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

@wuu

2015年学术文章

@zh-cn

2015年学术文章

@zh-hans

2015年学术文章

@zh-my

2015年学术文章

@zh-sg

2015年學術文章

@yue

2015年學術文章

@zh

2015年學術文章

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name

KN-93 inhibits IKr in mammalian cardiomyocytes.

@ast

KN-93 inhibits IKr in mammalian cardiomyocytes.

@en

type

Item

label

KN-93 inhibits IKr in mammalian cardiomyocytes.

@ast

KN-93 inhibits IKr in mammalian cardiomyocytes.

@en

prefLabel

KN-93 inhibits IKr in mammalian cardiomyocytes.

@ast

KN-93 inhibits IKr in mammalian cardiomyocytes.

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P1476

KN-93 inhibits IKr in mammalian cardiomyocytes.

@en

P2093

Leighton T Izu

http://www.w3.org/2001/XMLSchema#string

Rafael Shimkunas

http://www.w3.org/2001/XMLSchema#string

Ye Chen-Izu

http://www.w3.org/2001/XMLSchema#string

Zhong Jian

http://www.w3.org/2001/XMLSchema#string

P2860

Calmodulin-dependent protein kinase II: linking heart failure and arrhythmias

The newly synthesized selective Ca2+/calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells

Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.

Calmodulin kinase signaling in heart: an intriguing candidate target for therapy of myocardial dysfunction and arrhythmias.

Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II.

Sequential dissection of multiple ionic currents in single cardiac myocytes under action potential-clamp

Dynamics of the late Na(+) current during cardiac action potential and its contribution to afterdepolarizations.

CaMKII inhibitors: from research tools to therapeutic agents

KN-93 (2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine), a calcium/calmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated potassium channels.

Inhibitors of calmodulin-dependent protein kinase are nonspecific blockers of voltage-dependent K+ channels in vascular myocytes.

P304

173-176

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P31

scholarly article

P356

10.1016/J.YJMCC.2015.10.012

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P433

Pt B

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Bence Hegyi

Tamas Banyasz

P577

2015-10-10T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

282872732

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P698

26463508

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P932

4689637

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