Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production.
about
A gain-of-function mutation in STAT6Proinflammatory role for let-7 microRNAS in experimental asthmaJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.STAT6 and PARP Family Members in the Development of T Cell-dependent Allergic InflammationAirway fibrinogenolysis and the initiation of allergic inflammationIL-4 and IL-13 signaling in allergic airway diseaseConsequences of Stat6 deletion on Sis/PDGF- and IL-4-induced proliferation and transcriptional activation in murine fibroblastsCharacterization of cis-regulatory elements conferring mercury-induced interleukin-4 gene expression in rat mast cells: a role for signal transducer and activator of transcription 6 and TATA box binding sitesTransfer of in vivo primed transgenic T cells supports allergic lung inflammation and FIZZ1 and Ym1 production in an IL-4Rα and STAT6 dependent manner.Transplacental passage of interleukins 4 and 13?12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels.The use of knockouts to study determinants of airway hyperresponsiveness.Activated Natural Killer Cells Mediate the Suppressive Effect of Interleukin-4 on Tumor Development via STAT6 Activation in an Atopic Condition Melanoma Model.Aldose reductase inhibition prevents metaplasia of airway epithelial cells.Regulation of lymphocyte cell fate decisions and lymphomagenesis by BCL-6.Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer ProgressionAn alternate STAT6-independent pathway promotes eosinophil influx into blood during allergic airway inflammation.The adaptor protein insulin receptor substrate 2 inhibits alternative macrophage activation and allergic lung inflammationTrophic slime, allergic slime.New perspectives in asthma treatment.Importance of cytokines in murine allergic airway disease and human asthma.Gene knockout models of asthma.Small interfering RNA against transcription factor STAT6 leads to increased cholesterol synthesis in lung cancer cell lines.The effects of targeted deletion of cannabinoid receptors CB1 and CB2 on intranasal sensitization and challenge with adjuvant-free ovalbuminAdoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation.12/15-lipoxygenase is an interleukin-13 and interferon-γ counterregulated-mediator of allergic airway inflammation.What are the most promising strategies for the therapeutic immunomodulation of allergic diseases?Murine model of chronic human asthma.Distinct spatial requirement for eosinophil-induced airways hyperreactivity.Role of dendritic cells and Th2 lymphocytes in asthma: lessons from eosinophilic airway inflammation in the mouse.Role of interleukin-13 in fibrosis, particularly systemic sclerosis.Interleukin-5: a novel target for asthma therapy.Remodeling of the airway epithelium in asthma.IL-4 induced MUC4 enhancement in respiratory epithelial cells in vitro is mediated through JAK-3 selective signaling.Exclusion of IL-21 in the pathogenesis of OVA-induced asthma in mice.Is Th1 the solution for Th2 in asthma?JAK-STAT signaling in asthma.Modeling allergic asthma in mice: pitfalls and opportunities.src homology 2 domain-containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation.Absence of the common gamma chain (γ(c)), a critical component of the Type I IL-4 receptor, increases the severity of allergic lung inflammation.
P2860
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P2860
Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Signal transducer and activato ...... siveness and mucus production.
@ast
Signal transducer and activato ...... siveness and mucus production.
@en
type
label
Signal transducer and activato ...... siveness and mucus production.
@ast
Signal transducer and activato ...... siveness and mucus production.
@en
prefLabel
Signal transducer and activato ...... siveness and mucus production.
@ast
Signal transducer and activato ...... siveness and mucus production.
@en
P2093
P2860
P356
P1476
Signal transducer and activato ...... siveness and mucus production.
@en
P2093
B Schofield
D Kuperman
M J Grusby
M Wills-Karp
P2860
P304
P356
10.1084/JEM.187.6.939
P407
P577
1998-03-01T00:00:00Z