Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice - Wikidata - wikimedia - TriplyDB

Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice

Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice

http://www.wikidata.org/entity/Q36409544

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Emerging drugs of abuse: current perspectives on synthetic cannabinoids Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ(9)-THC: mechanism underlying greater toxicity?Vaping Synthetic Cannabinoids: A Novel Preclinical Model of E-Cigarette Use in Mice "Herbal incense": designer drug blends as cannabimimetics and their assessment by drug discrimination and other in vivo bioassays.Development of a high-performance liquid chromatography-tandem mass spectrometry method for the identification and quantification of CP-47,497, CP-47,497-C8 and JWH-250 in mouse brain.Cross-substitution of Δ9-tetrahydrocannabinol and JWH-018 in drug discrimination in rats.Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids.Baths salts, spice, and related designer drugs: the science behind the headlines.Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications.Drug-induced mitochondrial dysfunction and cardiotoxicity.Cannabinoids in disguise: Δ9-tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles.Ethanol induced acetylation of histone at G9a exon1 and G9a-mediated histone H3 dimethylation leads to neurodegeneration in neonatal mice.CB1 receptor-mediated signaling underlies the hippocampal synaptic, learning, and memory deficits following treatment with JWH-081, a new component of spice/K2 preparations In vitro and in vivo pharmacokinetics and metabolism of synthetic cannabinoids CUMYL-PICA and 5F-CUMYL-PICA.Tripping with Synthetic Cannabinoids ("Spice"): Anecdotal and Experimental Observations in Animals and Man.Distribution of Synthetic Cannabinoids JWH-210, RCS-4 and Δ 9-Tetrahydrocannabinol After Intravenous Administration to Pigs.A Fast and Comprehensive Analysis of 32 Synthetic Cannabinoids Using Agilent Triple Quadrupole LC-MS-MS.Synthetic Cathinone and Cannabinoid Designer Drugs Pose a Major Risk for Public Health.Natural (∆9-THC) and synthetic (JWH-018) cannabinoids induce seizures by acting through the cannabinoid CB1 receptor.Inhaled delivery of Δ(9)-tetrahydrocannabinol (THC) to rats by e-cigarette vapor technology.Synthetic Cannabinoids: Pharmacology, Behavioral Effects, and Abuse Potential.Evaluation of first generation synthetic cannabinoids on binding at non-cannabinoid receptors and in a battery of in vivo assays in mice.In vivo effects of synthetic cannabinoids JWH-018 and JWH-073 and phytocannabinoid Δ9-THC in mice: inhalation versus intraperitoneal injection.Acute and residual effects in adolescent rats resulting from exposure to the novel synthetic cannabinoids AB-PINACA and AB-FUBINACA.Neurocognition and subjective experience following acute doses of the synthetic cannabinoid JWH-018: a phase 1, placebo-controlled, pilot study.Pharmaco-toxicological effects of the novel third-generation fluorinate synthetic cannabinoids, 5F-ADBINACA, AB-FUBINACA, and STS-135 in mice. In vitro and in vivo studies.Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on "tetrad", sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies.Behavioral responses to acute and sub-chronic administration of the synthetic cannabinoid JWH-018 in adult mice prenatally exposed to corticosterone.Synthetic Cannabinoid Exposure: A New Risk for Children?Intracerebral Hemorrhage with Multiple Intracranial Arterial Stenoses in a Synthetic Cannabinoid "Spice" User.

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Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice

http://www.wikidata.org/entity/Q36409544

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年學術文章

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Inhalation exposure to smoke f ...... cannabimimetic effects in mice

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Inhalation exposure to smoke f ...... cannabimimetic effects in mice

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J.DRUGALCDEP.2012.05.034

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Drug and Alcohol Dependence

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Inhalation exposure to smoke f ...... cannabimimetic effects in mice

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Alphonse Poklis

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Aron H Lichtman

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Jason M Wiebelhaus

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Justin L Poklis

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Laura E Wise

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Robert E Vann

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P2860

Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

Cannabinergic aminoalkylindoles, including AM678=JWH018 found in 'Spice', examined using drug (Δ(9)-tetrahydrocannabinol) discrimination for rats

Withdrawal phenomena and dependence syndrome after the consumption of "spice gold"

JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist

Spice drugs as a new trend: mode of action, identification and legislation.

Synthetic cannabinoid JWH-018 and psychosis: an explorative study.

Central mediation and differential blockade by cannabinergics of the discriminative stimulus effects of the cannabinoid CB1 receptor antagonist rimonabant in rats

Determination of naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in mouse blood and tissue after inhalation exposure to 'buzz' smoke by HPLC/MS/MS.

Severe toxicity following synthetic cannabinoid ingestion.

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316-323

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10.1016/J.DRUGALCDEP.2012.05.034

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3

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126

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2012-07-07T00:00:00Z

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22776442

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3501554

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