Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.
about
Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targetsT cell epitopes and post-translationally modified epitopes in type 1 diabetesMolecular Interactions Governing Autoantigen Presentation in Type 1 DiabetesImmunogenetics of type 1 diabetes mellitusVasostatin-1 antigenic epitope mapping for induction of cellular and humoral immune responses to chromogranin A autoantigen in NOD miceImmune recognition of citrullinated epitopes.Molecules in medicine mini review: the αβ T cell receptor.Inhibition of Phosphoinositide 3-Kinase p110delta Does Not Affect T Cell Driven Development of Type 1 Diabetes Despite Significant Effects on Cytokine Production.N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetesCutting Edge: Nonobese Diabetic Mice Deficient in Chromogranin A Are Protected from Autoimmune Diabetes.Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusionNovel autoantigens for diabetogenic CD4 T cells in autoimmune diabetes.Pathogenic mechanisms in type 1 diabetes: the islet is both target and driver of disease.Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic mice.MHC Class II Protein Turnover In vivo and Its Relevance for Autoimmunity in Non-Obese Diabetic Mice.Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes.Narrowing in on the anti-β cell-specific T cells: looking 'where the action is'.Chromogranin A is a T cell antigen in human type 1 diabetes.Efficient Presentation of Multiple Endogenous Epitopes to Both CD4+ and CD8+ Diabetogenic T Cells for ToleranceDo post-translational beta cell protein modifications trigger type 1 diabetes?Molecular mechanisms for contribution of MHC molecules to autoimmune diseasesThe beta-cell in type 1 diabetes: What have we learned from proteomic studies?β cell ER stress and the implications for immunogenicity in type 1 diabetes.Inherent ER stress in pancreatic islet β cells causes self-recognition by autoreactive T cells in type 1 diabetesGlucagon-reactive islet-infiltrating CD8 T cells in NOD mice.Chromogranin A as biomarker in diabetes.Endoplasmic reticulum stress in beta cells and autoimmune diabetes.Chromogranin A Regulation of Obesity and Peripheral Insulin Sensitivity.Understanding type 1 diabetes through proteomics.Recognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes.Generation of β cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice.Environmental Factors Contribute to β Cell Endoplasmic Reticulum Stress and Neo-Antigen Formation in Type 1 Diabetes.CD40-mediated signalling influences trafficking, T-cell receptor expression, and T-cell pathogenesis, in the NOD model of type 1 diabetes.Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice.Tolerogenic Ag-PLG nanoparticles induce tregs to suppress activated diabetogenic CD4 and CD8 T cells.Understanding Autoimmune Diabetes through the Prism of the Tri-Molecular Complex.An insulin-IAPP hybrid peptide is an endogenous antigen for CD4 T cells in the non-obese diabetic mouse.Treatment of T1D via optimized expansion of antigen-specific Tregs induced by IL-2/anti-IL-2 monoclonal antibody complexes and peptide/MHC tetramers.Therapies to Suppress β Cell Autoimmunity in Type 1 Diabetes
P2860
Q26751244-89238905-5D16-41F6-BC52-CFC9BAB14957Q26787014-A8294CA2-D1B3-4668-9044-AF4C337AEED4Q28084487-BE6BB67C-A165-4F63-8E33-A1547AC0B013Q28087365-435AAF10-1ACB-4DE2-8052-FAB4B7261D2CQ28306169-533380A4-6E36-48CC-A663-15C0D1932B97Q30391892-072258C2-A584-4A75-BC4A-47DC7FC9F9F4Q34723826-C238C49A-1541-4C0E-8587-B64B103B9D8EQ35897436-499DB349-9E80-41D3-9880-797782153FA5Q36238365-F12278DD-CA81-4532-8C7F-1C462F61B0B7Q36387060-11667C11-D3D9-4032-9FBA-C92E09BFF775Q36945852-260009FA-4F2B-45F0-B42F-BF681409855DQ37018598-F14BB9D0-4378-4DA9-A6F9-BF72EEB9003CQ37088180-52928ECE-F068-4835-930E-F083DA052E79Q37274444-905AC42D-B207-41C3-9AFB-98B96D257093Q37338924-DA8DC888-1C5E-447B-B87C-9C59AB638A2BQ37478584-179C52A6-5E8E-4672-92AE-2C09D4FC7CF9Q37599880-4880F5F5-2C63-4A8F-887B-C7E26592F26CQ37698306-D5F0D8FF-B1E5-4EE1-BA55-5C5BFE28B3C9Q37716863-B5D3C84C-42AF-4083-A17E-BD0DF49A7E85Q37717905-62B37034-5E80-4FD4-81FA-4DD57FB5F8E1Q38139283-4CB8FD24-6E9A-46FA-8C0A-811D0AB297F0Q38248679-8AA6B2B2-3CAC-4672-8C1B-C9181DF1BC43Q38340362-4FEAA60F-EBE2-4D4A-BB46-89ADA536619AQ38637035-9F643D07-FADF-433B-99EA-11F85C75B186Q38771484-63D178DE-49AC-421A-A9BA-15B0445A64ABQ38946141-113A929B-F03F-4B10-BC58-9C3ADD3A41F6Q38950132-20D82225-0A0E-4B86-BBF8-1F5289FF3145Q38975660-93B1B4A4-2C7B-4B29-83C4-663FCF4F0900Q39147191-2D7449EE-304E-4A18-9A6E-8F8C11DBA193Q39398068-5E389346-CF14-49D7-A849-755CBBC07D90Q39499765-AC488C67-9FEB-450E-B04D-B83362EF3D8BQ42183951-C1205CB5-8567-4EF4-80D0-C74154548E87Q42369799-D1FA087D-4096-46E2-BE4E-6506A0462258Q46360981-7B2C16E0-5715-4DA3-A8E4-CB790949537FQ47133872-C05415BD-8B12-4F84-B841-7CDEF1B6E8F5Q47234002-F5FB372F-66A1-41D0-8B31-2B21DF789DA9Q49269317-EBE21423-9A66-431C-835E-EBC67168AF5BQ51350685-9D854CDF-D7CB-4A14-8A58-29E2FBE88D61Q55224664-A5170CA5-DD29-40B1-A92F-7CFE20207AF4Q58773667-A267F352-4E48-4EF2-8DB9-3DAD469A039E
P2860
Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.
@ast
Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.
@en
type
label
Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.
@ast
Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.
@en
prefLabel
Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.
@ast
Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.
@en
P2093
P2860
P356
P1433
P1476
Diabetogenic T-cell clones recognize an altered peptide of chromogranin A.
@en
P2093
Brenda Bradley
Gene Barbour
Kathryn Haskins
Rocky L Baker
Thomas Delong
P2860
P304
P356
10.2337/DB12-0112
P407
P577
2012-08-21T00:00:00Z