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Liver X receptors as integrators of metabolic and inflammatory signaling

Liver X receptors as integrators of metabolic and inflammatory signaling

http://www.wikidata.org/entity/Q36411128

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Molecular determinants of the interactions between SRC-1 and LXR/RXR heterodimers The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages Liver X receptors inhibit human monocyte-derived macrophage foam cell formation by inhibiting fluid-phase pinocytosis of LDL PPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1 Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease ApoE promotes the proteolytic degradation of Abeta Genome-wide association analysis of metabolic traits in a birth cohort from a founder population LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor Rab8-dependent recycling promotes endosomal cholesterol removal in normal and sphingolipidosis cells The nuclear receptor cofactor, receptor-interacting protein 140, is required for the regulation of hepatic lipid and glucose metabolism by liver X receptor Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFkappaB Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma Mesenchymal Stem Cells and Metabolic Syndrome: Current Understanding and Potential Clinical Implications Role of gut microbiota in the modulation of atherosclerosis-associated immune response Plant sterols as anticancer nutrients: evidence for their role in breast cancer The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity Cold Exposure Improves the Anti-diabetic Effect of T0901317 in Streptozotocin-Induced Diabetic Mice.Nuclear Receptors as Therapeutic Targets in Liver Disease: Are We There Yet?Liver X receptors at the intersection of lipid metabolism and atherogenesis Infection homeostasis: implications for therapeutic and immune programming of metabolism in controlling infection OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages Cathepsin D, a lysosomal protease, regulates ABCA1-mediated lipid efflux Role for phospholipid acyl chains and cholesterol in pulmonary infections and inflammation 2009 pandemic H1N1 influenza virus elicits similar clinical course but differential host transcriptional response in mouse, macaque, and swine infection models Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE A computational model for the analysis of lipoprotein distributions in the mouse: translating FPLC profiles to lipoprotein metabolism Loading into nanoparticles improves quercetin's efficacy in preventing neuroinflammation induced by oxysterols Oxysterol and diabetes activate STAT3 and control endothelial expression of profilin-1 via OSBP1 Pancreatic exocrine insufficiency in LXRbeta-/- mice is associated with a reduction in aquaporin-1 expression Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target Non-redundant roles for LXRalpha and LXRbeta in atherosclerosis susceptibility in low density lipoprotein receptor knockout mice.Deficiency of the NR4A neuron-derived orphan receptor-1 attenuates neointima formation after vascular injury Bifidobacteria can protect from enteropathogenic infection through production of acetate Liver X Receptors Link Lipid Metabolism and Inflammation.Liver X Receptor Agonist TO901317 Attenuates Paraquat-Induced Acute Lung Injury through Inhibition of NF-κB and JNK/p38 MAPK Signal Pathways.Macrophage-independent regulation of reverse cholesterol transport by liver X receptors.Tgif1 represses apolipoprotein gene expression in liver.

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Liver X receptors as integrators of metabolic and inflammatory signaling

http://www.wikidata.org/entity/Q36411128

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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2006年學術文章

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2006年學術文章

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name

Liver X receptors as integrators of metabolic and inflammatory signaling

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Liver X receptors as integrators of metabolic and inflammatory signaling

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Liver X receptors as integrators of metabolic and inflammatory signaling

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Liver X receptors as integrators of metabolic and inflammatory signaling

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Journal of Clinical Investigation

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Liver X receptors as integrators of metabolic and inflammatory signaling

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P2093

Noam Zelcer

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P2860

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

Role of LXRs in control of lipogenesis

Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein

An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

LXR, a nuclear receptor that defines a distinct retinoid response pathway

Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption.

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607-614

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scholarly article

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10.1172/JCI27883

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3

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