The role of Mg2+ in the inactivation of inwardly rectifying K+ channels in aortic endothelial cells.
about
Structural determinants of gating in inward-rectifier K+ channels.Lack of negatively charged residues at the external mouth of Kir2.2 channels enable the voltage-dependent block by external Mg2+.The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes.A conserved arginine residue in the pore region of an inward rectifier K channel (IRK1) as an external barrier for cationic blockers.Permeation and gating of an inwardly rectifying potassium channel. Evidence for a variable energy well.Unitary conductance variation in Kir2.1 and in cardiac inward rectifier potassium channels.Contribution of cytosolic cysteine residues to the gating properties of the Kir2.1 inward rectifier.Identification of a site involved in the block by extracellular Mg(2+) and Ba(2+) as well as permeation of K(+) in the Kir2.1 K(+) channel.
P2860
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P2860
The role of Mg2+ in the inactivation of inwardly rectifying K+ channels in aortic endothelial cells.
description
1995 nî lūn-bûn
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1995年の論文
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1995年学术文章
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1995年学术文章
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1995年学术文章
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1995年学术文章
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1995年学术文章
@zh-sg
1995年學術文章
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1995年學術文章
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1995年學術文章
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name
The role of Mg2+ in the inacti ...... s in aortic endothelial cells.
@ast
The role of Mg2+ in the inacti ...... s in aortic endothelial cells.
@en
type
label
The role of Mg2+ in the inacti ...... s in aortic endothelial cells.
@ast
The role of Mg2+ in the inacti ...... s in aortic endothelial cells.
@en
prefLabel
The role of Mg2+ in the inacti ...... s in aortic endothelial cells.
@ast
The role of Mg2+ in the inacti ...... s in aortic endothelial cells.
@en
P2860
P356
P1476
The role of Mg2+ in the inacti ...... s in aortic endothelial cells.
@en
P2093
P2860
P304
P356
10.1085/JGP.105.4.463
P577
1995-04-01T00:00:00Z