Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation
about
Clinical Overview of MDM2/X-Targeted TherapiesSurvivin, a molecular target for therapeutic interventions in squamous cell carcinoma.The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer.The multifaceted influence of histone deacetylases on DNA damage signalling and DNA repair.A potent hydroxamic acid-based, small-molecule inhibitor A452 preferentially inhibits HDAC6 activity and induces cytotoxicity toward cancer cells irrespective of p53 status.
P2860
Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Selective inhibition of histon ...... h MDM2 proteasomal degradation
@ast
Selective inhibition of histon ...... h MDM2 proteasomal degradation
@en
type
label
Selective inhibition of histon ...... h MDM2 proteasomal degradation
@ast
Selective inhibition of histon ...... h MDM2 proteasomal degradation
@en
prefLabel
Selective inhibition of histon ...... h MDM2 proteasomal degradation
@ast
Selective inhibition of histon ...... h MDM2 proteasomal degradation
@en
P2093
P2860
P356
P1433
P1476
Selective inhibition of histon ...... h MDM2 proteasomal degradation
@en
P2093
Chang-Sun Hwang
Hyun-Gyu Lee
In-Chul Park
Jae Youn Yi
Sang Taek Oh
Sang-Gu Hwang
Seok-Il Hong
Sung-Keum Seo
Tae-Boo Choe
Yun-Han Lee
P2860
P304
26528-26540
P356
10.18632/ONCOTARGET.3100
P407
P577
2014-12-31T00:00:00Z