Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists.
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The actin-bundling protein L-plastin supports T-cell motility and activationInternational Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug DevelopmenthCB2 ligand-interaction landscape: cysteine residues critical to biarylpyrazole antagonist binding motif and receptor modulation.A knockout mutation of a constitutive GPCR in Tetrahymena decreases both G-protein activity and chemoattraction.Depression-resistant endophenotype in mice overexpressing cannabinoid CB(2) receptorsInverse agonism and its therapeutic significance.Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists.Identification of raloxifene as a novel CB2 inverse agonist.Motor, visual and emotional deficits in mice after closed-head mild traumatic brain injury are alleviated by the novel CB2 inverse agonist SMM-189Immunoregulation of a CB2 receptor agonist in a murine model of neuroAIDSDesign and evaluation of a novel fluorescent CB2 ligand as probe for receptor visualization in immune cellsPlastin family of actin-bundling proteins: its functions in leukocytes, neurons, intestines, and cancerPreclinical evaluation of SMM-189, a cannabinoid receptor 2-specific inverse agonist.CNS effects of CB2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity.AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor.Rimonabant in rats with a metabolic syndrome: good news after the depression.Targeting the endocannabinoid system: to enhance or reduce?Emerging strategies for exploiting cannabinoid receptor agonists as medicines.Acetaminophen Use for Fever in Children Associated with Autism Spectrum DisorderMild Traumatic Brain Injury Produces Neuron Loss That Can Be Rescued by Modulating Microglial Activation Using a CB2 Receptor Inverse Agonist.CB2 cannabinoid receptor is a novel target for third-generation selective estrogen receptor modulators bazedoxifene and lasofoxifene.Chronic toxicology of cannabis.Cannabinoid receptor ligands as potential anticancer agents--high hopes for new therapies?Label-free screening assays: a strategy for finding better drug candidates.Endocannabinod Signal Dysregulation in Autism Spectrum Disorders: A Correlation Link between Inflammatory State and Neuro-Immune Alterations.The actin-bundling protein L-plastin: a critical regulator of immune cell function.Abnormalities in Dynamic Brain Activity Caused by Mild Traumatic Brain Injury Are Partially Rescued by the Cannabinoid Type-2 Receptor Inverse Agonist SMM-189.Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage.Anti-inflammatory cannabinoids in diet: Towards a better understanding of CB(2) receptor action?Characterization of the intrinsic activity for a novel class of cannabinoid receptor ligands: Indole quinuclidine analogs.Endocannabinoids produced upon action potential firing evoke a Cl(-) current via type-2 cannabinoid receptors in the medial prefrontal cortex.CB2 cannabinoid receptors: new vistas.Detailed characterisation of CB2 receptor protein expression in peripheral blood immune cells from healthy human volunteers using flow cytometry.Early phytocannabinoid chemistry to endocannabinoids and beyond.Regulation of cannabinoid CB2 receptor constitutive activity in vivo: repeated treatments with inverse agonists reverse the acute activation of JNK and associated apoptotic signaling in mouse brain.
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Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists.
@ast
Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists.
@en
type
label
Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists.
@ast
Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists.
@en
prefLabel
Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists.
@ast
Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists.
@en
P2093
P2860
P921
P356
P1476
Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists.
@en
P2093
D J Lundell
J A Kozlowski
R W Hipkin
P2860
P304
P356
10.1038/SJ.BJP.0707480
P407
P577
2007-10-01T00:00:00Z