AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors. - Wikidata - wikimedia - TriplyDB

AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors.

AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors.

http://www.wikidata.org/entity/Q36418127

about

Hypothetical gene C18orf42 encodes a novel protein kinase A-binding protein Direct association of the unique C-terminal tail of transmembrane AMPA receptor regulatory protein γ-8 with calcineurin Non-ionotropic signaling by the NMDA receptor: controversy and opportunity Therapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorder Regulation of the phosphatase PP2B by protein-protein interactions Signalling scaffolds and local organization of cellular behaviour Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in Striatum Calcineurin mediates synaptic scaling via synaptic trafficking of Ca2+-permeable AMPA receptors A calcineurin docking motif (LXVP) in dynamin-related protein 1 contributes to mitochondrial fragmentation and ischemic neuronal injury.A presynaptic role for PKA in synaptic tagging and memory.Propofol prevents electroconvulsive-shock-induced memory impairment through regulation of hippocampal synaptic plasticity in a rat model of depression Altered regulation of protein kinase a activity in the medial prefrontal cortex of normal and brain-injured animals actively engaged in a working memory task.The palmitoyl acyltransferase DHHC2 regulates recycling endosome exocytosis and synaptic potentiation through palmitoylation of AKAP79/150 Network compensation of cyclic GMP-dependent protein kinase II knockout in the hippocampus by Ca2+-permeable AMPA receptors.Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes A-kinase Anchoring Protein 79/150 Recruits Protein Kinase C to Phosphorylate Roundabout Receptors.Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice.Defective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease.Protein Kinase C (PKC)ζ Pseudosubstrate Inhibitor Peptide Promiscuously Binds PKC Family Isoforms and Disrupts Conventional PKC Targeting and Translocation.Reduction of increased calcineurin activity rescues impaired homeostatic synaptic plasticity in presenilin 1 M146V mutant.Protein kinase C gamma-mediated phosphorylation of GluA1 in the postsynaptic density of spinal dorsal horn neurons accompanies neuropathic pain, and dephosphorylation by calcineurin is associated with prolonged analgesia.Coordination of Protein Phosphorylation and Dephosphorylation in Synaptic Plasticity Localized calcineurin confers Ca2+-dependent inactivation on neuronal L-type Ca2+ channels.PLPP/CIN regulates bidirectional synaptic plasticity via GluN2A interaction with postsynaptic proteins Adenylyl cyclase anchoring by a kinase anchor protein AKAP5 (AKAP79/150) is important for postsynaptic β-adrenergic signaling.AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K(+) currents in ventricular myocytes following myocardial infarction.NMDA Receptor-Dependent LTD Requires Transient Synaptic Incorporation of Ca²⁺-Permeable AMPARs Mediated by AKAP150-Anchored PKA and Calcineurin The DEG/ENaC cation channel protein UNC-8 drives activity-dependent synapse removal in remodeling GABAergic neurons Adaptations in AMPA receptor transmission in the nucleus accumbens contributing to incubation of cocaine craving.AKAP signaling complexes: pointing towards the next generation of therapeutic targets?Calcium-permeable AMPA receptors in neonatal hypoxic-ischemic encephalopathy (Review)Autonomous CaMKII mediates both LTP and LTD using a mechanism for differential substrate site selection AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus.Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the β2-adrenergic receptor in neurons.Roles of subunit phosphorylation in regulating glutamate receptor function.Mechanisms and dynamics of AKAP79/150-orchestrated multi-protein signalling complexes in brain and peripheral nerve.A Place at the Table: LTD as a Mediator of Memory Genesis.How Ca2+-permeable AMPA receptors, the kinase PKA, and the phosphatase PP2B are intertwined in synaptic LTP and LTD.Optogenetic Control of Synaptic Composition and Function.A trans-synaptic nanocolumn aligns neurotransmitter release to receptors.

P2860

Q24317710-EAF5E921-27FF-4497-8774-5BA702C542FA Q24319854-C1E00068-F56F-48F5-9330-84599E4DF28C Q26745925-6B152F41-00AE-4EBE-842D-1C33CE18625C Q26797384-F4CCEEFC-1475-48FD-94AF-45F166E657D1 Q28076325-58B057B2-2064-48AC-A935-CC735EABF54D Q28259061-6D7D4A5D-8E6E-4ECC-9E4F-DA71F2B95412 Q28393596-41B01A49-AED1-47CC-B46D-C1BF1EC62F46 Q28507701-7593656C-1509-4877-A480-A8EBE4A01E6A Q30413675-F285FDAE-480D-4173-A67A-023BAABF5B1B Q34084438-753FEADC-B595-4AFF-94C9-572C5F4E1396 Q34274590-746BC995-C3CE-4B18-91D9-7F160F150D13 Q34918572-FA91519B-FBF1-42C8-958F-5F3753538AC8 Q34946082-9CC77DCF-459B-494D-B11E-9F16D01418E2 Q35189809-820C18B9-0924-4878-8E43-E23DEEAFE6DC Q35199477-6AF3A3E2-F79E-4805-BC28-4D5F1E78EA54 Q35662368-D7AB1D20-0A3B-4396-A3D0-D77AB2E3130A Q35742664-D176D866-2A88-46A6-A8AC-7CD7B00E40F6 Q35941413-FB27BCEF-FD34-4AA8-BDFC-44DAAD9ACBC7 Q36077719-BA1F94D6-67D2-4326-8D03-E245C97D029C Q36271540-D2A640E0-033F-41B2-AAAA-6D7B7BBF7F7B Q36299923-8696AE82-73BD-4FB1-8AE2-EDD2D05F78C8 Q36323396-21F844CE-58D2-492C-87D2-D566B3CB30E3 Q36672587-6EC69A05-ED9C-4175-B58F-0AD3DAFF8188 Q36925271-26E67B0D-10A1-4A29-9932-D16415350BDF Q36929153-13950F25-FD86-4537-B4B2-645A70FD7827 Q36992792-658E2E4C-BDFD-4BDC-82A1-B6F8D65CDDF0 Q37022458-EA5112C4-89D3-4E62-A8C8-27343BA273CA Q37165659-005574D6-2FC7-4646-B339-341C901B9665 Q37333137-E557FC16-4A19-4DAC-92A8-5746D0E05254 Q37427846-D9A867A4-35A3-4398-8D88-679D70381FF5 Q37565160-D3A7C116-1301-4D4C-9A1D-43AB51EBA6B9 Q37595519-95674F40-1F4F-4CB9-9BCF-E7D4A34B22D2 Q37637064-03C61A1E-8469-4479-9BE4-C438ED9E4FF4 Q37643798-E030886E-F4EF-473A-B797-7C0DA0B180D5 Q38167533-1D086E28-1182-4E17-927D-55D3A64CA8FE Q38344657-DC416F2F-F1EB-41C5-924A-8336CE9FB876 Q38494230-6A5440B9-6AE9-4BC4-816F-739B475A962D Q38818317-1D4D405F-4E60-464F-BD78-E46C0400987E Q38993097-253BE03A-383C-439A-8875-0E397CE5F058 Q39756886-53B0697D-6E74-4C71-A15D-E163E114E2D9

P2860

AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors.

http://www.wikidata.org/entity/Q36418127

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

AKAP150-anchored calcineurin r ...... Ca2+-permeable AMPA receptors.

@ast

AKAP150-anchored calcineurin r ...... Ca2+-permeable AMPA receptors.

@en

type

label

AKAP150-anchored calcineurin r ...... Ca2+-permeable AMPA receptors.

@ast

AKAP150-anchored calcineurin r ...... Ca2+-permeable AMPA receptors.

@en

prefLabel

AKAP150-anchored calcineurin r ...... Ca2+-permeable AMPA receptors.

@ast

AKAP150-anchored calcineurin r ...... Ca2+-permeable AMPA receptors.

@en

P1433

Q36418127-BCF71D41-84EC-467B-B881-00FC1985EB4A

P1476

Q36418127-D8FDB305-0F7A-4F75-824D-6EE970DFE602

P2093

Q36418127-8BA93D35-36D4-4F42-A1EF-9AA9782BC09D

Q36418127-9AF0C6C6-00B3-4279-850B-347DEA79DB5C

Q36418127-C534E185-1771-4E50-ADE3-A4EBF0D71530

Q36418127-D7FFCB93-FBA2-4CB0-BF6D-317A8CF0AA5B

Q36418127-DBC09CD9-3B77-49A2-932F-0D7F4D1B4164

Q36418127-EB0A8D9A-82E2-4E51-8AA9-010E80DB1645

P2860

Q36418127-01480206-1967-4D11-8AF1-26E2E08A66EE

Q36418127-03163230-C8CA-4F25-8BDC-5600F21EAC24

Q36418127-03314A4E-F7B8-40F7-BEF3-84B3D2AFACEE

Q36418127-0E824B78-8F53-416D-81EE-C4A2C367CCF9

Q36418127-17EF0726-C804-4E14-9BE7-BA85EC23FDBF

Q36418127-1C4F43BB-2619-4D5D-ADF0-222B1178261D

Q36418127-1CB8E82D-52CB-4AFE-A812-5458B4BD8649

Q36418127-1DD33F7F-F7A6-49A6-B898-60B081CA4856

Q36418127-1EAB8A32-CC58-4371-A911-6ED89AF5BF3D

Q36418127-1F7D5824-AD55-4A52-96A3-4241BFB7C923

P304

Q36418127-10EE102E-E818-4A82-8E0F-FB55FC98A171

P31

Q36418127-2EF26465-A2C3-49E5-B8B9-BEDF0DA05F5D

P356

Q36418127-00DFF74D-F795-4054-8BFA-0FCFE96F0107

P407

Q36418127-5DC5FA49-EEEE-42F8-971A-BF21A041427A

P433

Q36418127-721B9CDB-28B2-42A7-A738-FD8B984D3C39

P478

Q36418127-A98D618A-DFA2-4947-B5BE-772D201E6213

P50

Q36418127-FA393A41-A276-4324-A1DD-7E4398A4D991

P577

Q36418127-FF07A0E3-53E8-4170-A484-1AB10AEB6111

P698

Q36418127-67737C2E-047A-4DE8-A063-585BCCA05503

P932

Q36418127-B61194DD-2802-4B0C-9EBA-5E2AC6DE11E6

P356

JNEUROSCI.3326-12.2012

P1433

Journal of Neuroscience

P1476

AKAP150-anchored calcineurin r ...... Ca2+-permeable AMPA receptors

@en

P2093

Emily S Gibson

http://www.w3.org/2001/XMLSchema#string

Jennifer L Sanderson

http://www.w3.org/2001/XMLSchema#string

Jessica A Gorski

http://www.w3.org/2001/XMLSchema#string

Philip Lam

http://www.w3.org/2001/XMLSchema#string

Ronald K Freund

http://www.w3.org/2001/XMLSchema#string

Wallace S Chick

http://www.w3.org/2001/XMLSchema#string

P2860

Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade

Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase

AMPA receptor incorporation into synapses during LTP: the role of lateral movement and exocytosis.

Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia

Balanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signaling

Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex

Role for A kinase-anchoring proteins (AKAPS) in glutamate receptor trafficking and long term synaptic depression

Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression

AKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signaling

Regulation of A-kinase anchoring protein 79/150-cAMP-dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin

P304

15036-15052

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1523/JNEUROSCI.3326-12.2012

http://www.w3.org/2001/XMLSchema#string

P407

P433

43

http://www.w3.org/2001/XMLSchema#string

P478

32

http://www.w3.org/2001/XMLSchema#string

P50

Mark L Dell'Acqua

P577

2012-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23100425

http://www.w3.org/2001/XMLSchema#string

P932

3504485

http://www.w3.org/2001/XMLSchema#string