The NleE/OspZ family of effector proteins is required for polymorphonuclear transepithelial migration, a characteristic shared by enteropathogenic Escherichia coli and Shigella flexneri infections.
about
Shigella flexneri type III secretion system effectors OspB and OspF target the nucleus to downregulate the host inflammatory response via interactions with retinoblastoma proteinThe role of neutrophils in the event of intestinal inflammationThe type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements.The Shigella dysenteriae serotype 1 proteome, profiled in the host intestinal environment, reveals major metabolic modifications and increased expression of invasive proteins.The effector repertoire of enteropathogenic E. coli: ganging up on the host cellFecal leukocytes in children infected with diarrheagenic Escherichia coli.The Type III Effector NleD from Enteropathogenic Escherichia coli Differentiates between Host Substrates p38 and JNK.Distinct isoforms of phospholipase A2 mediate the ability of Salmonella enterica serotype typhimurium and Shigella flexneri to induce the transepithelial migration of neutrophils.Characterization of the ospZ promoter in Shigella flexneri and its regulation by VirB and H-NS.Pathogenesis of human enterovirulent bacteria: lessons from cultured, fully differentiated human colon cancer cell linesA type III effector antagonizes death receptor signalling during bacterial gut infection.Detection of enteric pathogens by the nodosome.Always one step ahead: How pathogenic bacteria use the type III secretion system to manipulate the intestinal mucosal immune system.Role of virulence factors on host inflammatory response induced by diarrheagenic Escherichia coli pathotypes.How Do the Virulence Factors of Shigella Work Together to Cause Disease?Prevalence and characteristics of the O122 pathogenicity island in typical and atypical enteropathogenic Escherichia coli strains.Identification of a Distinct Substrate-binding Domain in the Bacterial Cysteine Methyltransferase Effectors NleE and OspZ.The type III secretion effector NleE inhibits NF-kappaB activation.A distinct regulatory sequence is essential for the expression of a subset of nle genes in attaching and effacing Escherichia coli.Identification of novel substrates of Shigella T3SA through analysis of its virulence plasmid-encoded secretome.Evolutionary analysis and distribution of type III effector genes in pathogenic Escherichia coli from human, animal and food sources.
P2860
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P2860
The NleE/OspZ family of effector proteins is required for polymorphonuclear transepithelial migration, a characteristic shared by enteropathogenic Escherichia coli and Shigella flexneri infections.
description
2007 nî lūn-bûn
@nan
2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
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2007年學術文章
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name
The NleE/OspZ family of effect ...... Shigella flexneri infections.
@ast
The NleE/OspZ family of effect ...... Shigella flexneri infections.
@en
type
label
The NleE/OspZ family of effect ...... Shigella flexneri infections.
@ast
The NleE/OspZ family of effect ...... Shigella flexneri infections.
@en
prefLabel
The NleE/OspZ family of effect ...... Shigella flexneri infections.
@ast
The NleE/OspZ family of effect ...... Shigella flexneri infections.
@en
P2093
P2860
P921
P356
P1476
The NleE/OspZ family of effect ...... Shigella flexneri infections.
@en
P2093
Anthony T Maurelli
Beth A McCormick
Julia A Prentice
Karen L Mumy
Luminita Badea
P2860
P304
P356
10.1128/IAI.00684-07
P407
P577
2007-11-05T00:00:00Z