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Calcium modulates the generation of inositol 1,3,4-trisphosphate in human platelets by the activation of inositol 1,4,5-trisphosphate 3-kinaseSub-second oscillations of inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate during platelet activation by ADP and thrombin: lack of correlation with calcium kinetics.Anti-platelet activity of panaxatriol saponins is mediated by suppression of intracellular calcium mobilization and ERK2/p38 activation.Formation and metabolism of inositol 1,4,5-trisphosphate in human platelets.Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets.Harnessing the platelet signaling network to produce an optimal hemostatic response.ADP-induced platelet activation.Activation of phospholipase C and protein kinase C has little involvement in ADP-induced primary aggregation of human platelets: effects of diacylglycerols, the diacylglycerols, the diacylglycerol kinase inhibitor R59022, staurosporine and okadaic aPhosphorylation-dependent and -independent pathways of platelet aggregation.Spiking in cytosolic calcium concentration in single fibrinogen-bound fura-2-loaded human plateletsCa2+ mobilization primes protein kinase C in human platelets. Ca2+ and phorbol esters stimulate platelet aggregation and secretion synergistically through protein kinase C.Thrombin-induced inositol trisphosphate production by rabbit platelets is inhibited by ethanol.cADP-ribose formation by blood platelets is not responsible for intracellular calcium mobilization.
P2860
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P2860
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
ADP stimulates IP3 formation in human platelets.
@ast
ADP stimulates IP3 formation in human platelets.
@en
type
label
ADP stimulates IP3 formation in human platelets.
@ast
ADP stimulates IP3 formation in human platelets.
@en
prefLabel
ADP stimulates IP3 formation in human platelets.
@ast
ADP stimulates IP3 formation in human platelets.
@en
P2093
P2860
P1433
P1476
ADP stimulates IP3 formation in human platelets.
@en
P2093
P2860
P304
P356
10.1016/0014-5793(86)81000-6
P407
P577
1986-10-01T00:00:00Z