Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells.
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Oncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discoveryRegulation of Ketone Body Metabolism and the Role of PPARαEvaluation and prognostic significance of ACAT1 as a marker of prostate cancer progressionEthanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer preventionHMGCS2 enhances invasion and metastasis via direct interaction with PPARα to activate Src signaling in colorectal cancer and oral cancer.Lipid degradation promotes prostate cancer cell survival.The nutritional phenome of EMT-induced cancer stem-like cellsDeregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention.FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast.Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cellsA network-based pathway-expanding approach for pathway analysis.Genome-Wide Mapping of the Binding Sites and Structural Analysis of Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 2 Reveal that It Is a DNA-Binding Transcription Factor.Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cellsMitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin.Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment.CAF-like state in primary skin fibroblasts with constitutional BRCA1 epimutation sheds new light on tumor suppressor deficiency-related changes in healthy tissue.Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis.Autophagy in breast cancer and its implications for therapyMetabolic coupling in urothelial bladder cancer compartments and its correlation to tumor aggressiveness.Oncogenes and inflammation rewire host energy metabolism in the tumor microenvironment: RAS and NFκB target stromal MCT4.Altered Mitochondrial Signalling and Metabolism in Cancer.Molecular and diagnostic features of apocrine breast lesions.Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance.Encapsulation of human elastic cartilage-derived chondrocytes in nanostructured fibrin-agarose hydrogels.Metabolic Plasticity of Stem Cells and Macrophages in Cancer.Inactivation of HMGCL promotes proliferation and metastasis of nasopharyngeal carcinoma by suppressing oxidative stress.Fenofibrate Induces Ketone Body Production in Melanoma and Glioblastoma Cells.Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133+ tumor initiating cells.Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs).Cancer metabolism: new validated targets for drug discovery.Mitoketoscins: Novel mitochondrial inhibitors for targeting ketone metabolism in cancer stem cells (CSCs).Specific breast cancer prognosis-subtype distinctions based on DNA methylation patterns.Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation.Metabolic Reprogramming of Cancer Associated Fibroblasts: The Slavery of Stromal Fibroblasts.Metabolism and Epigenetic Interplay in Cancer: Regulation and Putative Therapeutic TargetsSystemic redox status in lung cancer patients is related to altered glucose metabolism
P2860
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P2860
Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Ketone bodies and two-compartm ...... is in epithelial cancer cells.
@ast
Ketone bodies and two-compartm ...... is in epithelial cancer cells.
@en
type
label
Ketone bodies and two-compartm ...... is in epithelial cancer cells.
@ast
Ketone bodies and two-compartm ...... is in epithelial cancer cells.
@en
prefLabel
Ketone bodies and two-compartm ...... is in epithelial cancer cells.
@ast
Ketone bodies and two-compartm ...... is in epithelial cancer cells.
@en
P2093
P2860
P50
P356
P1433
P1476
Ketone bodies and two-compartm ...... is in epithelial cancer cells.
@en
P2093
Anthony Howell
Ubaldo E Martinez-Outschoorn
P2860
P304
P356
10.4161/CC.22136
P577
2012-09-19T00:00:00Z