Cloning and expression of the isopenicillin N synthetase gene from Penicillium chrysogenum.
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Molecular regulation of beta-lactam biosynthesis in filamentous fungiMolecular characterization of the acyl-coenzyme A:isopenicillin N acyltransferase gene (penDE) from Penicillium chrysogenum and Aspergillus nidulans and activity of recombinant enzyme in Escherichia coliTrichothecene biosynthesis in Fusarium species: chemistry, genetics, and significanceCopurification and characterization of deacetoxycephalosporin C synthetase/hydroxylase from Cephalosporium acremoniumCharacterization of the Cephalosporium acremonium pcbAB gene encoding alpha-aminoadipyl-cysteinyl-valine synthetase, a large multidomain peptide synthetase: linkage to the pcbC gene as a cluster of early cephalosporin biosynthetic genes and evidenceThe isopenicillin N acyltransferases of Aspergillus nidulans and Penicillium chrysogenum differ in their ability to maintain the 40-kDa alphabeta heterodimer in an undissociated form.Quantitative analysis of Penicillium chrysogenum Wis54-1255 transformants overexpressing the penicillin biosynthetic genes.Microbial proline 4-hydroxylase screening and gene cloning.Cloning and characterization of the isopenicillin N synthase gene of Streptomyces griseus NRRL 3851 and studies of expression and complementation of the cephamycin pathway in Streptomyces clavuligerusExploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG productionBeta-lactam antibiotic biosynthetic genes have been conserved in clusters in prokaryotes and eukaryotes.A vacuolar membrane protein affects drastically the biosynthesis of the ACV tripeptide and the beta-lactam pathway of Penicillium chrysogenum.Analysis of the role of cysteine residues in isopenicillin N synthetase activity by site-directed mutagenesis.Organization of the biosynthesis genes for the peptide antibiotic gramicidin S.Cloning and characterization of beta-lactam biosynthetic genes.Gene cluster containing the genes for tyrocidine synthetases 1 and 2 from Bacillus brevis: evidence for an operon.Penicillin production in industrial strain Penicillium chrysogenum P2niaD18 is not dependent on the copy number of biosynthesis genes.Potential industrial use of cephalosporin biosynthetic enzymes and genes. An overview.Regulation and compartmentalization of β-lactam biosynthesis.Antibiotics--cloning of biosynthetic pathways.Molecular biology of penicillin and cephalosporin biosynthesis.Biosynthetic concepts for the production of β-lactam antibiotics in Penicillium chrysogenum.Peptide antibiotics, beta-lactams, and related compounds.A reporter gene analysis of penicillin biosynthesis gene expression in Penicillium chrysogenum and its regulation by nitrogen and glucose catabolite repression.Regulation of Aspergillus nidulans penicillin biosynthesis and penicillin biosynthesis genes acvA and ipnA by glucose.Cloning, characterization, and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase.Beta-lactam biosynthesis in a gram-negative eubacterium: purification and characterization of isopenicillin N synthase from Flavobacterium sp. strain SC 12.154.Cloning and expression in Escherichia coli of isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans.A nonribosomal system of peptide biosynthesis.Localization of the pathway of the penicillin biosynthesis in Penicillium chrysogenum.The cephamycin biosynthetic genes pcbAB, encoding a large multidomain peptide synthetase, and pcbC of Nocardia lactamdurans are clustered together in an organization different from the same genes in Acremonium chrysogenum and Penicillium chrysogenumThe Aspergillus nidulans npeA locus consists of three contiguous genes required for penicillin biosynthesisThe multifunctional peptide synthetase performing the first step of penicillin biosynthesis in Penicillium chrysogenum is a 421,073 dalton protein similar to Bacillus brevis peptide antibiotic synthetases.Modification of vertebrate and algal prolyl 4-hydroxylases and vertebrate lysyl hydroxylase by diethyl pyrocarbonate. Evidence for histidine residues in the catalytic site of 2-oxoglutarate-coupled dioxygenases.Factors affecting the isopenicillin N synthetase reaction.Improved expression of a hybrid Streptomyces clavuligerus cefE gene in Penicillium chrysogenum.High-level expression of the Streptomyces clavuligerus isopenicillin N synthase gene in Escherichia coli.Production of cephalosporin intermediates by feeding adipic acid to recombinant Penicillium chrysogenum strains expressing ring expansion activity.Functional analysis of conserved histidine residues in Cephalosporium acremonium isopenicillin N synthase by site-directed mutagenesis.Collagen Hydroxylases and the Protein Disulfide Isomerase Subunit of Prolyl 4-Hydroxylases
P2860
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P2860
Cloning and expression of the isopenicillin N synthetase gene from Penicillium chrysogenum.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
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1986年學術文章
@zh-hant
name
Cloning and expression of the ...... from Penicillium chrysogenum.
@ast
Cloning and expression of the ...... from Penicillium chrysogenum.
@en
type
label
Cloning and expression of the ...... from Penicillium chrysogenum.
@ast
Cloning and expression of the ...... from Penicillium chrysogenum.
@en
prefLabel
Cloning and expression of the ...... from Penicillium chrysogenum.
@ast
Cloning and expression of the ...... from Penicillium chrysogenum.
@en
P2093
P1433
P1476
Cloning and expression of the ...... from Penicillium chrysogenum.
@en
P2093
Ingolia TD
Queener SW
Scheetz ME 2nd
Skatrud PL
P304
P356
10.1016/0378-1119(86)90084-3
P407
P577
1986-01-01T00:00:00Z