Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus.
about
Isolation and characterization of a beta-lactamase-inhibitory protein from Streptomyces clavuligerus and cloning and analysis of the corresponding geneCloning and characterization of the isopenicillin N synthase gene of Streptomyces griseus NRRL 3851 and studies of expression and complementation of the cephamycin pathway in Streptomyces clavuligerusCloning and location of a gene governing lysine epsilon-aminotransferase, an enzyme initiating beta-lactam biosynthesis in Streptomyces spp.Chromosome-specific recombinant DNA libraries from the fungus Aspergillus nidulans.Beta-lactam antibiotic biosynthetic genes have been conserved in clusters in prokaryotes and eukaryotes.The enzymes of β-lactam biosynthesis.The improving prospects for yield increase by genetic engineering in antibiotic-producing Streptomycetes.Molecular analysis of a beta-lactam resistance gene encoded within the cephamycin gene cluster of Streptomyces clavuligerus.Cloning and characterization of beta-lactam biosynthetic genes.Precursor flux control through targeted chromosomal insertion of the lysine epsilon-aminotransferase (lat) gene in cephamycin C biosynthesis.Identification and Characterization of the Sulfazecin Monobactam Biosynthetic Gene Cluster.Potential industrial use of cephalosporin biosynthetic enzymes and genes. An overview.Antibiotics--cloning of biosynthetic pathways.Molecular biology of penicillin and cephalosporin biosynthesis.Origins of the β-lactam rings in natural products.The beta-lactam biosynthesis genes for isopenicillin N epimerase and deacetoxycephalosporin C synthetase are expressed from a single transcript in Streptomyces clavuligerus.Complete nucleotide sequence of a linear plasmid from Streptomyces clavuligerus and characterization of its RNA transcriptsCloning and sequencing of the beta-lactam hydroxylase gene (cefF) from Streptomyces clavuligerus: gene duplication may have led to separate hydroxylase and expandase activities in the actinomycetes.Cloning, characterization, and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase.Streptomyces lipmanii expresses two restriction systems that inhibit plasmid transformation and bacteriophage plaque formationBeta-lactam biosynthesis in a gram-negative eubacterium: purification and characterization of isopenicillin N synthase from Flavobacterium sp. strain SC 12.154.Cloning and expression in Escherichia coli of isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans.Interdependence of gene expression for early steps of cephalosporin synthesis in Streptomyces clavuligerus.The cephamycin biosynthetic genes pcbAB, encoding a large multidomain peptide synthetase, and pcbC of Nocardia lactamdurans are clustered together in an organization different from the same genes in Acremonium chrysogenum and Penicillium chrysogenumThe Aspergillus nidulans npeA locus consists of three contiguous genes required for penicillin biosynthesisModification of vertebrate and algal prolyl 4-hydroxylases and vertebrate lysyl hydroxylase by diethyl pyrocarbonate. Evidence for histidine residues in the catalytic site of 2-oxoglutarate-coupled dioxygenases.High-level expression of the Streptomyces clavuligerus isopenicillin N synthase gene in Escherichia coli.Analysis of rate-limiting reactions in cephalosporin biosynthesis.Functional analysis of conserved histidine residues in Cephalosporium acremonium isopenicillin N synthase by site-directed mutagenesis.
P2860
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P2860
Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus.
description
1988 nî lūn-bûn
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1988年の論文
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1988年学术文章
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1988年学术文章
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1988年学术文章
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1988年学术文章
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1988年学术文章
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1988年學術文章
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1988年學術文章
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1988年學術文章
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name
Cloning and nucleotide sequenc ...... rom Streptomyces clavuligerus.
@ast
Cloning and nucleotide sequenc ...... rom Streptomyces clavuligerus.
@en
type
label
Cloning and nucleotide sequenc ...... rom Streptomyces clavuligerus.
@ast
Cloning and nucleotide sequenc ...... rom Streptomyces clavuligerus.
@en
prefLabel
Cloning and nucleotide sequenc ...... rom Streptomyces clavuligerus.
@ast
Cloning and nucleotide sequenc ...... rom Streptomyces clavuligerus.
@en
P2093
P1433
P1476
Cloning and nucleotide sequenc ...... rom Streptomyces clavuligerus.
@en
P2093
Aharonowitz Y
Mevarech M
Westlake DW
P304
P356
10.1016/0378-1119(88)90557-4
P407
P577
1988-01-01T00:00:00Z