Activation of Torpedo acetylcholine receptors expressed in mouse fibroblasts. Single channel current kinetics reveal distinct agonist binding affinities.
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Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunitEpibatidine activates muscle acetylcholine receptors with unique site selectivity.Hidden Markov modeling for single channel kinetics with filtering and correlated noiseEnd-plate acetylcholine receptor: structure, mechanism, pharmacology, and diseaseFundamental gating mechanism of nicotinic receptor channel revealed by mutation causing a congenital myasthenic syndromeKinetic determinants of agonist action at the recombinant human glycine receptorDecrypting the sequence of structural events during the gating transition of pentameric ligand-gated ion channels based on an interpolated elastic network modelGating Movement of Acetylcholine Receptor Caught by Plunge-FreezingInhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent CationsCongenital myasthenic syndromes: pathogenesis, diagnosis, and treatmentCongenital myasthenic syndromes due to heteroallelic nonsense/missense mutations in the acetylcholine receptor epsilon subunit gene: identification and functional characterization of six new mutationsPrinciples of agonist recognition in Cys-loop receptorsRecent advances in Cys-loop receptor structure and functionDefinition of two agonist types at the mammalian cold-activated channel TRPM8Mutations in the M4 domain of Torpedo californica acetylcholine receptor dramatically alter ion channel function.Conotoxins targeting nicotinic acetylcholine receptors: an overviewAcetylcholine receptor channels activated by a single agonist molecule.Inversion of Markov processes to determine rate constants from single-channel data.Two-dimensional components and hidden dependencies provide insight into ion channel gating mechanisms.The dissociation of acetylcholine from open nicotinic receptor channelsModels of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites.Inorganic, monovalent cations compete with agonists for the transmitter binding site of nicotinic acetylcholine receptorsBarium permeability of neuronal nicotinic receptor alpha 7 expressed in Xenopus oocytes.Opening rate of acetylcholine receptor channels.Open channel noise. VI. Analysis of amplitude histograms to determine rapid kinetic parameters.Analysis of cyclic and acyclic nicotinic cholinergic agonists using radioligand binding, single channel recording, and nuclear magnetic resonance spectroscopy.Diffusion model in ion channel gating. Extension to agonist-activated ion channelsElectrostatic interactions regulate desensitization of the nicotinic acetylcholine receptor.Ligand-induced conformational change in the alpha7 nicotinic receptor ligand binding domainNicotinic acetylcholine receptor and the structural basis of neuromuscular transmission: insights from Torpedo postsynaptic membranesMenthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward.Roles of amino acids and subunits in determining the inhibition of nicotinic acetylcholine receptors by competitive antagonists.Detection and trapping of intermediate states priming nicotinic receptor channel opening.Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor.Agonist-induced closure of constitutively open gamma-aminobutyric acid channels with mutated M2 domains.Estimating binding affinities of the nicotinic receptor for low-efficacy ligands using mixtures of agonists and two-dimensional concentration-response relationshipsFixation of allosteric states of the nicotinic acetylcholine receptor by chemical cross-linking.Shaker potassium channel gating. III: Evaluation of kinetic models for activation.Naturally occurring mutations at the acetylcholine receptor binding site independently alter ACh binding and channel gating.Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules bound
P2860
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P2860
Activation of Torpedo acetylcholine receptors expressed in mouse fibroblasts. Single channel current kinetics reveal distinct agonist binding affinities.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
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1990年學術文章
@zh
1990年學術文章
@zh-hant
name
Activation of Torpedo acetylch ...... ct agonist binding affinities.
@ast
Activation of Torpedo acetylch ...... ct agonist binding affinities.
@en
type
label
Activation of Torpedo acetylch ...... ct agonist binding affinities.
@ast
Activation of Torpedo acetylch ...... ct agonist binding affinities.
@en
prefLabel
Activation of Torpedo acetylch ...... ct agonist binding affinities.
@ast
Activation of Torpedo acetylch ...... ct agonist binding affinities.
@en
P2093
P356
P1476
Activation of Torpedo acetylch ...... ct agonist binding affinities.
@en
P2093
P304
P356
10.1085/JGP.96.2.395
P577
1990-08-01T00:00:00Z